Outcome of convulsive status epilepticus: a review

Novorol, Claire L; Chin, Richard; Scott, Rod C.

doi:10.1136/adc.2006.107516

Cited by 50 publications

(53 citation statements)

References 64 publications

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“…Animal studies have shown that protracted seizures are harmful and may result in brain injury (1). Human studies show that the longer the duration of seizures, the more difficult their treatment (1). Such data argue for prompt detection and treatment of seizures in their early stages.…”

Section: Discussionmentioning

confidence: 99%

A case of near‐drowning: a case for routine cerebral monitoring

et al. 2010

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Section: Discussionmentioning

confidence: 99%

A case of near‐drowning: a case for routine cerebral monitoring

et al. 2010

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“…The study was large ( n = 11 580), subtle SE (which features high mortality rates) was excluded and this might explain why these findings were very different from prior results. Estimates in children appear to be lower, with case‐fatality rates between 2.7% and 5.2% for younger populations, and up to 13% for adolescents 103 . The most common cause of GCSE in children is febrile convulsive SE, which has a negligible morbidity and mortality 104 …”

Section: Outcomes and Complicationsmentioning

confidence: 99%

“…Even with a prolonged febrile convulsion, the rate of subsequent epilepsy is 10 times higher than for the general population 110 . Animal studies have found that SE causes hippocampal damage, including oedema and injury, predisposing to recurrent seizures 103 …”

Section: Outcomes and Complicationsmentioning

confidence: 99%

Review article: Convulsive and non‐convulsive status epilepticus: An emergency medicine perspective

Shah

Vashi

Jagoda

2009

Emerg Medicine Australasia

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Status epilepticus (SE) is divided into convulsive and non-convulsive types; both are associated with significant morbidity and mortality. Although convulsive SE is easily recognized, non-convulsive SE remains an elusive diagnosis as physical signs are varied and subtle. Successful management depends on a comprehensive approach that involves diagnostic testing and pharmacological interventions while ensuring cerebral oxygenation and perfusion at all times. There are a limited number of well-designed studies to support the development of evidence-based recommendations for the management of SE, especially for the management of non-convulsive status. Benzodiazepines, specifically lorazepam, continue to be the most commonly recommended first-line therapy; best treatment for refractory status cases depends on resources available and must be tailored to the individual institution. In order to facilitate care, it is recommended that each institution develop a management protocol for these patients.

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“…Paediatric population‐based data on CSE report a mortality rate of 3%, 1 and data from a select population with refractory CSE in a paediatric intensive care setting report a mortality to 32% 4 . Morbidity secondary to childhood CSE includes the development of focal neurological deficits, cognitive impairment and behavioural problems 5 . The management of CSE is time critical: the longer CSE lasts, the more difficult it is to terminate 5–11 .…”

mentioning

confidence: 99%