Outcome of cold coagulation for the treatment of cervical intraepithelial neoplasia in a department of genitourinary medicine.

Survey of colposcopy service provided by genito‐urinary medicine in England and Wales

“…The debate as to whether to use ablative or excisional methods for treatment of CIN exists within genito‐urinary medicine as it does within gynaecology. The management of CIN within genito‐urinary medicine clinics is influenced by the outcome of research both by gynaecolgists (Duncan 1981; Jordan 1985; Prendiville 1989) and genito‐urinary medicine physicians (Williams 1990; Edwards 1990).…”

Treatment of precancerous cervical lesions

“…Cure rates comparable with those of cryotherapy and laser ablation have been reported from large case series: cure rates exceeding 96% for CIN 1; 94% for CIN 2; and 90% for CIN 3 have been reported [21][22][23][24].…”

Advances in Cervical Cancer Management

“…A meta-analysis consisting of 41 studies found PET or PET/CT to have the highest pooled sensitivity and specificity compared with CT or MRI when detecting metastatic LNs in cervical cancer [21]. Para-aortic LN (PALN) SUV max ≥3.3 was a significant prognostic factor in patients with advanced squamous cell carcinomas of the cervix [23]. The results showed that PET-based nomograms performed better than the FIGO stage alone in predicting recurrence-free survival, disease-specific survival and overall survival [22].…”

“…In certain clinical situations, such as bulky lesions, a narrow vaginal apex, inability to enter the cervical os, extension to the lateral parametria or pelvic sidewall, and lower vaginal extension, interstitial brachytherapy may achieve a better dose distribution than intracavitary methods and may be the treatment of choice [23]. The data on clinical outcomes from interstitial brachytherapy despite its use for many years are limited to small series and a very heterogeneous group of patients.…”

“…It consists of the removal of at least two pelvic organs: anterior (bladder and uterus); posterior (uterus and rectum) or; total (both compartments). In case of a lateropelvic recurrence, a laterally extended endopelvic resection can be successfully performed with acceptable morbidity and interesting survival results [23]. Reconstruction of the pelvic floor, by means of musculocutaneous, omental flaps or human cellular dermal matrix [22], with or without colpoplasty, is important to fill the empty pelvis and prevent bowel occlusion or fistula.…”