Outcome of antenatally diagnosed abdominal wall defects

Abstract

Objective To examine the natural history and detailed outcome of antenatally diagnosed abdominal wall defects. Methods

Predictive factors at birth of the severity of gastroschisis

“…Although the survival rate for babies born with GS has improved and is now practically 85%, short and long-term morbidity is still a serious problem. The mortality rate reported in recent literature varies greatly (2.4% to 11%) [15,16] . but the mortality rate reported in our study (11.7%) tallies with the values reported in most studies.…”

Neonatal Surgery

“…strictures or atresias associated with the defect. Primary closure gives the best outcomes, but this is not always possible without causing a devastating increase in intra-abdominal pressure with splinting of the diaphragm, so a staged or silo closure is then preferred 8,9 . Mortality in this group of patients is related to sepsis as well as associated malformations.…”

The role of three-dimensional ultrasound in the differential diagnosis of omphalocele and gastroschisis

“…3,10,11 The survival of the gastroschisis and omphalocele cases has increased from 60% during the 1960s to more than 90% currently. The parenteral nutritional, surgical and the anesthetic management techniques are improved.…”

“…However, the wound closure difficulties and the gastrointestinal dysfunctions are still the cause of the long-term morbidities for gastroschisis. 1,11 Elevation of the maternal serum alpha-feto protein levels is associated with the abdominal wall defects, although the levels are greater in the gastroschisis than in the omphalocele. Acetyl cholinesterase and pseudo cholinesterase rise may help to differentiate the sipina bifida from the rise of the alpha-feto protein observed in abdominal wall defects.…”

“…Generally, the detection and the differential diagnosis ratios of the two entities are high but isolated cases may be missed. 3,5,[11][12][13] In cases with difficulty to identify the exact pathology and to demonstrate the co-existing pathologies, the 3D ultrasound may be helpful. Besides its help as a diagnostic tool, the 3D ultrasound may help the family to understand and realize the situation.…”