Outcome and Quality of Life Favour a Conservative Treatment of Patients with Primary Gastric Lymphoma

Abstract

Long-term outcome of patients with gastric lymphoma is excellent irrespective of the lymphoma type and the treatment approach. Considering quality of life a conservative therapeutic strategy should be favoured.

Long term quality of life in conservatively treated gastric lymphoma patients versus gastrectomized patients and gastritis patients

“…A 2011 study comparing the two types of treatments using the Gastro Intestinal Quality of Life Index (GLQI) found that, after treatment for gastric lymphoma, "Posttherapeutic quality of life was generally high with a significant advantage for patients treated conservatively compared to those who underwent surgery" [17]. Showing a more favorable outcome of quality of life after chemotherapy compared to after a gastrectomy for gastric lymphoma patients.…”

“…The results also support the findings of a 2011 study that concluded, "long-term outcome of patients with gastric lymphoma is excellent irrespective of the lymphoma type and the treatment approach. Considering quality of life a conservative therapeutic strategy should be favored" [17].…”

“…Using the San Francisco 36-item questionnaire (SF36) and Gastrointestinal Quality of Life Index (GLQI), Fischbach et al, found superior quality of life among patients treated conservatively [17]. Local experience, confirmed by others elsewhere, noted occasions in which conservative antilymphoma therapies can yield situations with very poor gastric emptying and poor quality of life.…”

MALT Lymphoma: Forget Surgery?

“…There are two strong arguments for such a recommendation: equal treatment outcomes after surgical or conservative strategies and a better quality of life with a stomach-preserving therapy. The latter has been clearly demonstrated by a prospective randomized trial with a 10-year follow-up [15]. …”

MALT-Lymphom

“…Bei fehlender Überlegenheit der Chirurgie gegenüber den konservativen Therapieverfahren wiegt der Aspekt der Lebensqualität nach organerhaltender Therapie schwerer stellt ein eindeutiges Argument gegen die chirurgische Resektion dar [20]. Eine Operation ist heute nur noch bei Komplikationen wie einer endoskopisch nicht beherrschbaren Blutung oder Perforation indiziert.…”