2013
DOI: 10.1186/cc13084
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Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery

Abstract: IntroductionDelirium is an acute disturbance of consciousness and cognition that has been shown to be associated with poor outcomes, including increased mortality. We aimed to evaluate outcome after postoperative delirium in a cohort of surgical intensive care unit (SICU) patients.MethodsThis prospective study was conducted over a 10-month period in a SICU. Postoperative delirium was diagnosed in accordance with the Intensive Care Delirium Screening Checklist (ICDSC). The primary outcome was mortality at 6-mon… Show more

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Cited by 188 publications
(140 citation statements)
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“…The occurrence of delirium is associated with increased morbidity and mortality, prolonged hospital stay, worse functional recovery, and long-term decline in cognitive function. 1,2 In patients admitted to hospital, around 30-40% of delirium cases are thought to be attributable to modifi able risk factors, and are therefore preventable. 3 Various approaches aimed at minimising the infl uence of risk factors in medical patients have not improved outcomes, and there are no conclusive studies that support pharmacological prophylaxis.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…The occurrence of delirium is associated with increased morbidity and mortality, prolonged hospital stay, worse functional recovery, and long-term decline in cognitive function. 1,2 In patients admitted to hospital, around 30-40% of delirium cases are thought to be attributable to modifi able risk factors, and are therefore preventable. 3 Various approaches aimed at minimising the infl uence of risk factors in medical patients have not improved outcomes, and there are no conclusive studies that support pharmacological prophylaxis.…”
Section: Introductionmentioning
confidence: 99%
“…3 Various approaches aimed at minimising the infl uence of risk factors in medical patients have not improved outcomes, and there are no conclusive studies that support pharmacological prophylaxis. 4 Dexmedetomidine is a highly selective α 2 adrenoreceptor agonist that provides anxiolysis, sedation, and modest analgesia with minimal respiratory depression. 5 Dexmedetomidine is increasingly used for sedation in mechanically ventilated patients in the intensive care unit (ICU), 6 where its use is associated with a decreased prevalence of delirium when compared with other sedatives.…”
Section: Introductionmentioning
confidence: 99%
“…Consequences of delirium continue to afflict patients even after hospital discharge. Patients with delirium are more likely to be readmitted to the hospital, to require institutionalization, develop cognitive dysfunction, and have decreased quality of life as compared to those that did not develop delirium (4)(5)(6)(7)(8)(9)(10)(11)(12)(13). The impact that delirium has on healthcare costs and patient outcomes has led to a number of interventions to prevent it or reduce its duration, but unfortunately the high prevalence of delirium persists despite these attempts.…”
mentioning
confidence: 99%
“…월 동안 사망률이 2.5배 높았고, 퇴원 후 일상생활기능의 감소 도 2.2배 높았으며 (Abelha et al, 2013), 재원기간도 평균 4 일 이상 길게 보고되었다 (Robinson et al, 2009) (Robinson et al, 2009;Staus, 2011;van Meenen, van Meenen, de Rooij, & ter Riet, 2014), 고령으로 인한 취약한 기저질환 동반 (Inouye et al, 2014), 수술 후 지연되는 신체 회복 상태 (Bellelli et al, 2014), 수술로 인해 발생하는 기동력 장애 (Chung et al, 2011), 수술 후 발생하는 심각한 통증 (Staus, 2011) (Sykes, 2012).…”
Section: 수술 후 섬망이 발생한 환자는 발생하지 않은 환자에 비해 6개unclassified