Outcome and Associated Factors among Adult Tetanus Patients Admitted to Jimma University Medical Center: A Retrospective Study

Tekle, Enisha; Mehertab, Markos; Lamba, Dheeraj; Moren, Rebecca; Bagilkar, Vinod V.

doi:10.9734/jpri/2021/v33i34b31847

Cited by 2 publications

(1 citation statement)

References 4 publications

(10 reference statements)

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“…[ 12 ] In this study, only 5 patients had received the vaccine, indicating lower coverage than reported elsewhere. [ 13 , 14 ] The reason is that 89.01% of the patients in this study are farmers, 94.51% live in rural areas, 75.82% are middle-aged and elderly people. The low vaccination rate is attributed to the inadequate medical resources and insufficient awareness of prevention among middle-aged and elderly individuals in rural areas.…”

Section: Discussionmentioning

confidence: 95%

Adult patients with tetanus in Anhui Province of China from 2013 to 2022: A retrospective study

Cheng,

Liang,

Miaomiao

et al. 2023

Medicine

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Tetanus is a highly fatal infectious disease with an incubation period of 7 to 8 days. The aim of this study was to identify risk factors for death in tetanus patients, develop a nomogram model for predicting mortality risk. This retrospective study included tetanus patients who were admitted to the intensive care unit department between January 2013 and December 2022. The patients were divided into 2 groups based on their final outcome, namely death group and survival group. Risk factors associated with mortality were analyzed using univariate and multivariate logistic regression analysis. Finally, a nomogram model was developed using the rms package. A total of 91 patients were enrolled in this study, including 54 males and 37 females. The average age of the tetanus patients was 52.88 ± 16.56 years, with a mean incubation period of 8.51 ± 3.97 days. The foot was the most common injury site (42.86%), and metal product stabbing was the leading cause of injury (48.78%). Ventilator-associated pneumonia was the most frequent complication (21.98%). Univariate and multivariate logistic regression analyses revealed that Ablett classification (odds ratio [OR], 21.999; 95% confidence interval [CI], 4.124–117.352), white blood cell count (OR, 6.033; 95%CI, 1.275–28.552), and autonomic nervous dysfunction (OR, 22.663; 95%CI, 4.363–117.728) as independent risk factors for tetanus patients. The C-index of the nomogram model was 0.942, with an area under the curve of the receiver operating characteristic curve at 0.942 (95%CI, 0.871–0.905). Ablett classification, white blood cell count, autonomic nervous dysfunctions were associated with the prognosis of patients with tetanus. The nomogram model developed based on risk factors has high accuracy.

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Section: Discussionmentioning

confidence: 95%

Adult patients with tetanus in Anhui Province of China from 2013 to 2022: A retrospective study

Cheng,

Liang,

Miaomiao

et al. 2023

Medicine

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Exploring Spatial Variation of Women’s Tetanus Vaccination in Ethiopia: Spatial Analysis of Ethiopian Demographic and Health Survey 2016

Belay,

mulugeta,

Agegn

et al. 2024

SAGE Open

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Tetanus is a bacterial infection that causes painful muscular contractions throughout the body, usually starting in the jaw. Every year, 15,000 to 30,000 maternal deaths occur due to tetanus related to the delivery process. Exploring variations of women’s tetanus immunization is crucial for programmers’ planning and monitoring. As a result, this study aims to evaluate the spatial distribution of women’s tetanus vaccination coverage and risk areas of women’s tetanus vaccination clustering in Ethiopia. The study used Ethiopian Demographic and Health Survey data, which was conducted in 2016 using the Ethiopia Population and Housing Census 2007 sampling frame. From 15,683 women aged 15 to 49, a sample of 7,193 women was selected using eligible criteria. This study used spatial data analysis. To determine geographical danger zones for tetanus vaccination of women, cluster, hotspot analysis, spatial interpolation, and spatial scan statistics were used. At the regional level of Ethiopia, tetanus vaccination was spatially clustered (Global Moran’s I = 0.066, p = .0001). Western Tigray, eastern SNNP, and northern Oromia were identified as hotspots of poor tetanus vaccine coverage, whereas western Oromia, Afar, and southeast Amhara regions were designated as non-risky areas of Ethiopia. The spatial Bayesian kriging interpolation analysis predicted high-risk areas were the southwestern and eastern parts of Oromia, western Tigray, Harari, and Dire Dawa Western Tigray, the eastern SNNP, southern Amhara, and northern Oromia have been recognized as a significant hotspot. Health workers, programmers, government, and non-governmental organizations in Ethiopia will implement spatially based strategic interventions for women’s tetanus immunization.

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Outcome and Associated Factors among Adult Tetanus Patients Admitted to Jimma University Medical Center: A Retrospective Study

Cited by 2 publications

References 4 publications

Adult patients with tetanus in Anhui Province of China from 2013 to 2022: A retrospective study

Adult patients with tetanus in Anhui Province of China from 2013 to 2022: A retrospective study

Exploring Spatial Variation of Women’s Tetanus Vaccination in Ethiopia: Spatial Analysis of Ethiopian Demographic and Health Survey 2016

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