“…The average duration of latency plus infectious periods (D) was considered as median time to VRE acquisition after admission, on the basis of observational data in outbreak setting, 17 that applied the duration of 5 days for R 0 calculation. R 0 ranged from 1.02 to 1.99 in the studies selected, 12,[18][19][20][21][22][23][24][25][26] and the pooled R 0 , found after weighting by population proportions in every outbreak, was 1.32 (interquartile range, 1.03-1.46) ( Figure 3). R 0 tended to increase with time (Spearman rank order correlation: R = 0.46, P = .11).…”