Outbreak of Salmonella Newport linked to imported frozen cooked crayfish in dill brine, Sweden, July to November 2019

Mörk, Marie Jansson; Karamehmedovic, Nadja; Hansen, Anette Tarp; Öhd, Joanna Nederby; Lindblad, M.; Östlund, Emma; Rehn, Moa; Jernberg, Cecilia

doi:10.2807/1560-7917.es.2022.27.22.2100918

Cited by 3 publications

(1 citation statement)

References 25 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Salmonella including S. Typhimurium has also been linked to human illnesses and outbreaks stemming from the consumption or handling of contaminated shellfish (e.g. oysters, clams, mussels and crayfish) [8,10,11]. Among these, the highest risk is posed by raw shellfish, such as oysters.…”

Section: Introductionmentioning

confidence: 99%

Characterization of MLST-99 Salmonella Typhimurium and the monophasic variant I:4,[5],12:i:- isolated from Canadian Atlantic coast shellfish

Hodges,

Cooper,

Koziol

et al. 2024

Microbiology

View full text Add to dashboard Cite

Salmonella enterica subsp. enterica Typhimurium and its monophasic variant I 1;4,[5],12:i:- (MVST) are responsible for thousands of reported cases of salmonellosis each year in Canada, and countries worldwide. We investigated S. Typhimurium and MVST isolates recovered from raw shellfish harvested in Atlantic Canada by the Canadian Food Inspection Agency (CFIA) over the past decade, to assess the potential impact of these isolates on human illness and to explore possible routes of shellfish contamination. Whole-genome sequence analysis was performed on 210 isolates of S. Typhimurium and MVST recovered from various food sources, including shellfish. The objective was to identify genetic markers linked to ST-99, a sequence type specifically associated with shellfish, which could explain their high prevalence in shellfish. We also investigated the genetic similarity amongst CFIA ST-99 isolates recovered in different years and geographical locations. Finally, the study aimed to enhance the molecular serotyping of ST-99 isolates, as they are serologically classified as MVST but are frequently misidentified as S. Typhimurium through sequence analysis. To ensure recovery of ST-99 from shellfish was not due to favourable growth kinetics, we measured the growth rates of these isolates relative to other Salmonella and determined that ST-99 did not have a faster growth rate and/or shorter lag phase than other Salmonella evaluated. The CFIA ST-99 isolates from shellfish were highly clonal, with up to 81 high-quality single nucleotide variants amongst isolates. ST-99 isolates both within the CFIA collection and those isolated globally carried numerous unique deletions, insertions and mutations in genes, including some considered important for virulence, such as gene deletions in the type VI secretion system. Interestingly, several of these genetic characteristics appear to be unique to North America. Most notably was a large genomic region showing a high prevalence in genomes from Canadian isolates compared to those from the USA. Although the functions of the majority of the proteins encoded within this region remain unknown, the genes umuC and umuD, known to be protective against UV light damage, were present. While this study did not specifically examine the effects of mutations and insertions, results indicate that these isolates may be adapted to survive in specific environments, such as ocean water, where wild birds and/or animals serve as the natural hosts. Our hypothesis is reinforced by a global phylogenetic analysis, which indicates that isolates obtained from North American shellfish and wild birds are infrequently connected to isolates from human sources. These findings suggest a distinct ecological niche for ST-99, potentially indicating their specialization and adaptation to non-human hosts and environments, such as oceanic habitats.

show abstract

Section: Introductionmentioning

confidence: 99%

Characterization of MLST-99 Salmonella Typhimurium and the monophasic variant I:4,[5],12:i:- isolated from Canadian Atlantic coast shellfish

Hodges,

Cooper,

Koziol

et al. 2024

Microbiology

View full text Add to dashboard Cite

show abstract

Human Salmonellosis: A Continuous Global Threat in the Farm-to-Fork Food Safety Continuum

Al-Hindi

Albiheyri

Alharbi

et al. 2023

Foods

View full text Add to dashboard Cite

Salmonella is one of the most common zoonotic foodborne pathogens and a worldwide public health threat. Salmonella enterica is the most pathogenic among Salmonella species, comprising over 2500 serovars. It causes typhoid fever and gastroenteritis, and the serovars responsible for the later disease are known as non-typhoidal Salmonella (NTS). Salmonella transmission to humans happens along the farm-to-fork continuum via contaminated animal- and plant-derived foods, including poultry, eggs, fish, pork, beef, vegetables, fruits, nuts, and flour. Several virulence factors have been recognized to play a vital role in attaching, invading, and evading the host defense system. These factors include capsule, adhesion proteins, flagella, plasmids, and type III secretion systems that are encoded on the Salmonella pathogenicity islands. The increased global prevalence of NTS serovars in recent years indicates that the control approaches centered on alleviating the food animals’ contamination along the food chain have been unsuccessful. Moreover, the emergence of antibiotic-resistant Salmonella variants suggests a potential food safety crisis. This review summarizes the current state of the knowledge on the nomenclature, microbiological features, virulence factors, and the mechanism of antimicrobial resistance of Salmonella. Furthermore, it provides insights into the pathogenesis and epidemiology of Salmonella infections. The recent outbreaks of salmonellosis reported in different clinical settings and geographical regions, including Africa, the Middle East and North Africa, Latin America, Europe, and the USA in the farm-to-fork continuum, are also highlighted.

show abstract

Investigation of salmonellosis during and after the COVID-19 pandemic (2020-2023)

I. E. Badasyan,

R.V. Nushikyan

2023

Res. Biotechnol. Environ. Sci.

View full text Add to dashboard Cite

With the Coronavirus disease pandemic in 2020-2023, salmonella distribution has gained great concerted attention since COVID-19 treatment and salmonellosis was conditioned by antibiotics.The present study aimed to investigate the incidence and clinical characteristics of Salmonellosis (salmonellosis gastroenteritis infection) in Armenia during the COVID-19 pandemic, between 2020 and 2023, without age restrictions. The genus Salmonella was identified using biochemical tests and serological methods at Laboratories of Armenia. Near 100 stool samples ere cultured on SS agar and selenite aquatic agar. The study identified 57 infected cases with Salmonella species and the majority of infection was in Yerevan people (n = 37 patients). The oldest patient was 71 years old from the Stepanavan region. Common symptoms included high temperature, diarrhea, restraint, weakness, pus residue in stool, unformed stool, headache, and dizziness. Two children from the same family were infected with Salmonella during the study. The patients were treated with different antibiotics for 3-10 days, with rifampicin, cephalosporins (2nd and 3rd generation), and carbapenems being the most commonly administrated drugs. The antibiotic susceptibility index was determined using the EUCAST documents. After the antibiotic therapy, the patients' health was monitored for a month. Additionally, the study found the Extended Spectrum Beta-Lactamase (ESBL) enzymes in newborn, 10-year-old, and 33-year-old patients.

show abstract

Outbreak of Salmonella Newport linked to imported frozen cooked crayfish in dill brine, Sweden, July to November 2019

Cited by 3 publications

References 25 publications

Characterization of MLST-99 Salmonella Typhimurium and the monophasic variant I:4,[5],12:i:- isolated from Canadian Atlantic coast shellfish

Characterization of MLST-99 Salmonella Typhimurium and the monophasic variant I:4,[5],12:i:- isolated from Canadian Atlantic coast shellfish

Human Salmonellosis: A Continuous Global Threat in the Farm-to-Fork Food Safety Continuum

Investigation of salmonellosis during and after the COVID-19 pandemic (2020-2023)

Contact Info

Product

Resources

About