Outbreak of Pseudomonas aeruginosa infections in a neonatal care unit associated with feeding bottles heaters

Molina‐Cabrillana, Jesús; Artiles, Fernando; Dorta-Hung, Elena; Santana-Reyes, Candelaria; Quori, A.; Lafarga-Capuz, Bernardo; Hernández-Vera, J.R.

doi:10.1016/j.ajic.2012.08.004

Cited by 7 publications

(2 citation statements)

References 8 publications

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“…In most investigated outbreaks, water was implicated either directly or indirectly. For example, devices that were previously in contact with contaminated tap water (Blanc, Parret, Janin, Raselli, & Francioli, ; Molina‐Cabrillana et al., ) and hand washing with contaminated tap water (Bert et al., ; Ferroni et al., ) were traced back as the source of contamination in hospital settings. In some cases, up to 42% of the strains that caused invasive infections in intensive care units (ICUs) originated from water (Blanc et al., ; Reuter, Sigge, Wiedeck, & Trautmann, ) and were the principal source of colonization in patients, with over 60% of tap water samples positive for P. aeruginosa (Vallés et al., ).…”

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confidence: 99%

Pseudomonas aeruginosa in premise plumbing of large buildings

2016

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Pseudomonas aeruginosa is an opportunistic bacterial pathogen that is widely occurring in the environment and is recognized for its capacity to form or join biofilms. The present review consolidates current knowledge on P. aeruginosa ecology and its implication in healthcare facilities premise plumbing. The adaptability of P. aeruginosa and its capacity to integrate the biofilm from the faucet and the drain highlight the role premise plumbing devices can play in promoting growth and persistence. A meta‐analysis of P. aeruginosa prevalence in faucets (manual and electronic) and drains reveals the large variation in device positivity reported and suggest the high variability in the sampling approach and context as the main reason for this variation. The effects of the operating conditions that prevail within water distribution systems (disinfection, temperature, and hydraulic regime) on the persistence of P. aeruginosa are summarized. As a result from the review, recommendations for proactive control measures of water contamination by P. aeruginosa are presented. A better understanding of the ecology of P. aeruginosa and key influencing factors in premise plumbing are essential to identify culprit areas and implement effective control measures.

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Section: Introductionmentioning

confidence: 99%

Pseudomonas aeruginosa in premise plumbing of large buildings

2016

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“…3 Multiple P. aeruginosa outbreaks have been documented in NICUs and have been attributed to contaminated medications, respiratory equipment, laryngoscopes, and personnel hand contamination. [4][5][6][7][8][9][10][11][12] Pseudomonas aeruginosa outbreaks have also been associated with contaminated hospital tap water [11][12][13][14] because the organism is hardy and can form biofilms in plumbing fixtures that resist chemical treatment. 15 In fall 2013, a P. aeruginosa outbreak involving 15 patients and 2 deaths occurred in a 28-bed NICU that admits 370-450 patients/year.…”

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Pseudomonas aeruginosa Outbreak in a Neonatal Intensive Care Unit Attributed to Hospital Tap Water

Kinsey

Koirala

Solomon

et al. 2017

Infect. Control Hosp. Epidemiol.

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OBJECTIVE To investigate an outbreak of Pseudomonas aeruginosa infections and colonization in a neonatal intensive care unit. DESIGN Infection control assessment, environmental evaluation, and case-control study. SETTING Newly built community-based hospital, 28-bed neonatal intensive care unit. PATIENTS Neonatal intensive care unit patients receiving care between June 1, 2013, and September 30, 2014. METHODS Case finding was performed through microbiology record review. Infection control observations, interviews, and environmental assessment were performed. A matched case-control study was conducted to identify risk factors for P. aeruginosa infection. Patient and environmental isolates were collected for pulsed-field gel electrophoresis to determine strain relatedness. RESULTS In total, 31 cases were identified. Case clusters were temporally associated with absence of point-of-use filters on faucets in patient rooms. After adjusting for gestational age, case patients were more likely to have been in a room without a point-of-use filter (odds ratio [OR], 37.55; 95% confidence interval [CI], 7.16-∞). Case patients had higher odds of exposure to peripherally inserted central catheters (OR, 7.20; 95% CI, 1.75-37.30) and invasive ventilation (OR, 5.79; 95% CI, 1.39-30.62). Of 42 environmental samples, 28 (67%) grew P. aeruginosa. Isolates from the 2 most recent case patients were indistinguishable by pulsed-field gel electrophoresis from water-related samples obtained from these case-patient rooms. CONCLUSIONS This outbreak was attributed to contaminated water. Interruption of the outbreak with point-of-use filters provided a short-term solution; however, eradication of P. aeruginosa in water and fixtures was necessary to protect patients. This outbreak highlights the importance of understanding the risks of stagnant water in healthcare facilities. Infect Control Hosp Epidemiol 2017;38:801-808.

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Literatur-Update zu Ausbrüchen auf neonatologischen Intensivpflegestationen – Serratia marcescens, Klebsiella pneumoniae, Acinetobacter baumannii und Pseudomonas aeruginosa

Kraus-Haas

Mielke

Simon

2015

Bundesgesundheitsbl.

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Häufungen von Infektionen mit einem (vermeintlich) einheitlichen Erreger in neonatologischen Intensivpflegestationen (NICUs) sind unerwünschte Ereignisse, durch die die Sicherheit der Patienten und ein günstiger Ausgang der Intensivtherapie gefährdet wird [1]. Mitunter sterben die Kinder an unmittelbaren Komplikationen bzw. langfristigen Folgen dieser "Late-onset"-Infektionen oder ihre psychomotorischen und mentalen Entwicklungsoptionen werden durch diese Ereignisse nachhaltig beeinträchtigt [2]. Ausbrüche bedingen zudem erhebliche Mehrbelastungen des Behandlungsteams (zu dem wir auch das Hygienefachpersonal zählen) [3] und können zur vorüber-gehenden oder dauerhaften Schließung einer Abteilung führen [4][5][6][7][8]. Aufgrund der besonderen Infektionsgefährdung der Patienten, der strukturell-organisatorischen Besonderheiten der Intensivtherapie in NICUs, des initial sehr uncharakteristischen klinischen Bildes und aufgrund des speziellen Erregerspektrums (z. B. Serratia marcescens) müssen Ausbrüche auf NICUs separat von anderen Ausbrüchen betrachtet werden [1].Die

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Outbreak of Pseudomonas aeruginosa infections in a neonatal care unit associated with feeding bottles heaters

Cited by 7 publications

References 8 publications

Pseudomonas aeruginosa in premise plumbing of large buildings

Pseudomonas aeruginosa in premise plumbing of large buildings

Pseudomonas aeruginosa Outbreak in a Neonatal Intensive Care Unit Attributed to Hospital Tap Water

Literatur-Update zu Ausbrüchen auf neonatologischen Intensivpflegestationen – Serratia marcescens, Klebsiella pneumoniae, Acinetobacter baumannii und Pseudomonas aeruginosa

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