Outbreak of methylisothiazolinone allergy targeting those aged ≥40 years

Methylisothiazolinone contact allergy in Croatia: Epidemiology and course of disease following patch testing

“…In the current investigation, most reactions were caused by consumer products. This is also reflected in the fact that many more females than males were allergic to MI (2.1% males; 11.0% females), which is also seen in other populations …”

Descriptive Study of Sensitization to Methylchloroisothiazolinone and Methylisothiazolinone in a Skin Allergy Unit

“…Our data are consistent with those of Lundov et al, 13 who found a greater frequency of sensitization to MCI/MI and MI in women aged more than 40 years, with lesions on the hands and face. Similarly, McFadden et al 19 found higher rates of sensitization to MI in women aged 40 years, with lesions located on the face. The fact that the face is one of the most frequently involved sites could be explained in part by the fact that cosmetic products are the main source of sensitization.…”

Methylisothiazolinone allergy in the paediatric population: the epidemic begins?

“…The literature supports the anxiety over an increase in the frequency of allergy and sensitization to MCI/MI in the adult population, with a forecast of an epidemic . Some European countries have shown a twofold increase in frequency, perhaps due to the potential for MI to cause allergic reactions via airborne exposure, predominantly from paint .…”

“…Some European countries have shown a twofold increase in frequency, perhaps due to the potential for MI to cause allergic reactions via airborne exposure, predominantly from paint . It is also thought that this allergen specifically targets an adult population …”