Outbreak of Listeria <i>ivanovii abortion</i> in sheep in India

Chand, Puran; Sadana, J. R.

doi:10.1136/vr.145.3.83

Cited by 37 publications

(20 citation statements)

References 7 publications

(11 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Experimental studies and field cases of Listeria infections in humans and animals in Indian subcontinent have been reviewed by Malik et al (2002), usually documented as sporadic cases but occasionally as disease outbreaks. Chand and Sadana (1998) reported L. ivanovii-induced abortion in sheep. L. ivanovii and L. monocytogenes have also been recovered from mastitis cases in cattle and buffalo (Rawool et al 2007).…”

Section: Epidemiology Transmission and Spreadmentioning

confidence: 96%

Listeriosis in animals, its public health significance (food-borne zoonosis) and advances in diagnosis and control: a comprehensive review

Dhama

Karthik

Tiwari

et al. 2015

Veterinary Quarterly

116

108

View full text Add to dashboard Cite

Listeriosis is an infectious and fatal disease of animals, birds, fish, crustaceans and humans. It is an important food-borne zoonosis caused by Listeria monocytogenes, an intracellular pathogen with unique potential to spread from cell to cell, thereby crossing blood-brain, intestinal and placental barriers. The organism possesses a pile of virulence factors that help to infect the host and evade from host immune machinery. Though disease occurrence is sporadic throughout the world, it can result in severe damage during an outbreak. Listeriosis is characterized by septicaemia, encephalitis, meningitis, meningoencephalitis, abortion, stillbirth, perinatal infections and gastroenteritis with the incubation period varying with the form of infection. L. monocytogenes has been isolated worldwide from humans, animals, poultry, environmental sources like soil, river, decaying plants, and food sources like milk, meat and their products, seafood and vegetables. Since appropriate vaccines are not available and infection is mainly transmitted through foods in humans and animals, hygienic practices can prevent its spread. The present review describes etiology, epidemiology, transmission, clinical signs, post-mortem lesions, pathogenesis, public health significance, and advances in diagnosis, vaccines and treatment of this disease. Special attention has been given to novel as well as prospective emerging therapies that include bacteriophage and cytokine therapy, avian egg yolk antibodies and herbal therapy. Various vaccines, including advances in recombinant and DNA vaccines and their modes of eliciting immune response, are also discussed. Due focus has also been given regarding appropriate prevention and control strategies to be adapted for better management of this zoonotic disease.

show abstract

Section: Epidemiology Transmission and Spreadmentioning

confidence: 96%

Listeriosis in animals, its public health significance (food-borne zoonosis) and advances in diagnosis and control: a comprehensive review

Dhama

Karthik

Tiwari

et al. 2015

Veterinary Quarterly

116

108

View full text Add to dashboard Cite

show abstract

“…However, the high mortality rate of about 20-30% in those developing listeriosis (pregnant women, elderly, and immunocompromised persons) makes L. monocytogenes a serious human pathogen (Farber and Peterkin, 1991;Mead et al, 1999). Listeriosis in animals is predominantly a foodborne disease which is often transmitted by consumption of spoiled silage causing abortions, stillbirths, and neonatal septicemia in sheep and cattle (Alexander et al, 1992;Chand and Sadana, 1999;Dennis, 1975;Gill, 1937;Ramage et al, 1999;Sergeant et al, 1991;Wesley, 1999).…”

Section: Introductionmentioning

confidence: 97%

Pathogenomics of Listeria spp.

Hain

Chatterjee

Ghai

et al. 2007

International Journal of Medical Microbiology

View full text Add to dashboard Cite

“…L. ivanovii (formerly known as L. monocytogenes serotype 5) was first isolated in Bulgaria in 1955 from lambs with congenital listeriosis (299). Human cases of L. ivanovii infection are rare (116), the vast majority of reported isolations of this species being from abortions, stillbirths, and neonatal septicemias in sheep and cattle (4,90,134,529,610,693). A third species, L. seeligeri, is considered nonpathogenic (555), although it has been implicated in at least one case of human listeriosis (556).…”

Section: Introductionmentioning

confidence: 99%

ListeriaPathogenesis and Molecular Virulence Determinants

et al. 2001

View full text Add to dashboard Cite

The gram-positive bacterium Listeria monocytogenes is the causative agent of listeriosis, a highly fatal opportunistic foodborne infection. Pregnant women, neonates, the elderly, and debilitated or immunocompromised patients in general are predominantly affected, although the disease can also develop in normal individuals. Clinical manifestations of invasive listeriosis are usually severe and include abortion, sepsis, and meningoencephalitis. Listeriosis can also manifest as a febrile gastroenteritis syndrome. In addition to humans, L. monocytogenes affects many vertebrate species, including birds. Listeria ivanovii, a second pathogenic species of the genus, is specific for ruminants. Our current view of the pathophysiology of listeriosis derives largely from studies with the mouse infection model. Pathogenic listeriae enter the host primarily through the intestine. The liver is thought to be their first target organ after intestinal translocation. In the liver, listeriae actively multiply until the infection is controlled by a cell-mediated immune response. This initial, subclinical step of listeriosis is thought to be common due to the frequent presence of pathogenic L. monocytogenes in food. In normal indivuals, the continual exposure to listerial antigens probably contributes to the maintenance of anti-Listeria memory T cells. However, in debilitated and immunocompromised patients, the unrestricted proliferation of listeriae in the liver may result in prolonged low-level bacteremia, leading to invasion of the preferred secondary target organs (the brain and the gravid uterus) and to overt clinical disease. L. monocytogenes and L. ivanovii are facultative intracellular parasites able to survive in macrophages and to invade a variety of normally nonphagocytic cells, such as epithelial cells, hepatocytes, and endothelial cells. In all these cell types, pathogenic listeriae go through an intracellular life cycle involving early escape from the phagocytic vacuole, rapid intracytoplasmic multiplication, bacterially induced actin-based motility, and direct spread to neighboring cells, in which they reinitiate the cycle. In this way, listeriae disseminate in host tissues sheltered from the humoral arm of the immune system. Over the last 15 years, a number of virulence factors involved in key steps of this intracellular life cycle have been identified. This review describes in detail the molecular determinants of Listeria virulence and their mechanism of action and summarizes the current knowledge on the pathophysiology of listeriosis and the cell biology and host cell responses to Listeria infection. This article provides an updated perspective of the development of our understanding of Listeria pathogenesis from the first molecular genetic analyses of virulence mechanisms reported in 1985 until the start of the genomic era of Listeria research

show abstract

Outbreak of Listeria ivanovii abortion in sheep in India

Cited by 37 publications

References 7 publications

Listeriosis in animals, its public health significance (food-borne zoonosis) and advances in diagnosis and control: a comprehensive review

Listeriosis in animals, its public health significance (food-borne zoonosis) and advances in diagnosis and control: a comprehensive review

Pathogenomics of Listeria spp.

ListeriaPathogenesis and Molecular Virulence Determinants

Contact Info

Product

Resources

About