Outbreak of Human Metapneumovirus Infection in Norwegian Children

Døllner, Henrik; Risnes, Kari; Radtke, Andreas; Nordbø, Svein Arne

doi:10.1097/01.inf.0000126401.21779.74

Cited by 119 publications

(92 citation statements)

References 13 publications

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“…These findings are consistent with other studies, which have demonstrated a higher prevalence of hMPV infections in spring and late winter [12,16,21,27,28]. Interestingly, in the French [8], Dutch [11] and Norwegian studies [19], hMPV was found at a higher rate in December and January. Owing to an inability to collect samples during December in the current study, the incidence of infection compared with the other respiratory viruses detected elsewhere, could not be completely assessed.…”

Section: Discussionsupporting

confidence: 82%

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The Role of Human Metapneumovirus in Pediatric Respiratory Tract Infection in Qatar

Althani¹,

Azzam

Abboubaker

et al. 2010

Future Virol.

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Aim: The human metapneumovirus (hMPV) has been recently discovered as an etiological agent of acute respiratory infections in infants and children, with similar clinical symptoms to those caused by respiratory syncytial virus. The aim of this study was to determine the prevalence of hMPV and its potential role as a causative agent of respiratory tract infections in children in Qatar. Methods: In the present study, we examined 84 nasopharyngeal aspirates from children with respiratory tract infections, presenting at Al-Saad Pediatric Emergency Center in Doha, Qatar, as outpatients, for the presence of respiratory viruses. Results: A total of 56 out of 84 (66.7%) cases were positive for the presence of respiratory viruses. Out of the 56 positive cases 54 (96%) contained hMPV; whereas 12 out of 56 (21.4%) contained human parainfluenza virus. A total of 14 out of 56 of the positive patients were infected with more than one virus. hMPV was in samples infected with one or more respiratory tract infection viruses and was the most frequently isolated virus from infants less than 6 months of age. Conclusion: This is the first report demonstrating the prevalence of hMPV in children suffering from respiratory tract infections in Qatar. Detection of this virus may have significant clinical implications in this patient population in Qatar.

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Section: Discussionsupporting

confidence: 82%

“…The incidence of hMPV-associated LRTI in young children varies with geographical location and time of year, and can range from 5 to 15% [12][13][14][15][16][17][18]. However, higher rates have also been reported [19,20]. hMPV infections are associated with hospitalization of children [15,16,[21][22][23].…”

mentioning

confidence: 97%

The Role of Human Metapneumovirus in Pediatric Respiratory Tract Infection in Qatar

Althani¹,

Azzam

Abboubaker

et al. 2010

Future Virol.

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“…showing that hMPV has both seasonal and annual distribution (8,(12)(13)(14)(15). in a study by caracciolo et al (13), the incidence of hMPV infection was 25. in our study, all hMPV-positive children, 2 hospitalized and 6 non-hospitalized, were diagnosed with bronchiolitis.…”

Section: -2009 This Finding Is Consistent With Previous Datamentioning

confidence: 99%

“…in a study by caracciolo et al (13), the incidence of hMPV infection was 25. in our study, all hMPV-positive children, 2 hospitalized and 6 non-hospitalized, were diagnosed with bronchiolitis. hMPV has thus far been identified in children with either upper or lower respiratory tract infection or both, asthma exacerbation, croup, or influenza-like illness (4,9,8,12,(14)(15)(16). Bronchiolitis is the most common diagnosis in children identified as having hMPV infection, while upper respiratory infection, pneumonia and asthma exacerbations have been reported less frequently (4,8,(12)(13)(14)(15).…”

Section: -2009 This Finding Is Consistent With Previous Datamentioning

confidence: 99%

Detection of human metapneumovirus in infants with acute respiratory tract infection

Mammas¹

2011

Mol Med Rep

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Abstract. Both respiratory syncytial virus (rSV) and human metapneumovirus (hMPV), a recently discovered respiratory pathogen classified in the Paramyxoviridae family, have been associated with acute respiratory tract infections (arTi) in infants. The aim of our study was to determine the incidence and clinical features of hMPV infection in infants presenting with arTi at a tertiary children's hospital in Greece during the 2007-2008 and 2008-2009 winter seasons. routine nasal swabs were obtained from 127 infants younger than 12 months of age. The specimens were tested for the presence of hMPV and rSV antigens using validated enzyme-linked immunoassays. The mean age of the studied infants was 3 months (range 19 days to 12 months). hMPV was detected in 8 (6.3%) children, 4 boys and 4 girls, while rSV was detected in 39 (30.7%) children, 22 boys and 17 girls. in 7 children, hMPV was identified as a unique viral pathogen, while only 1 child was co-infected with hMPV and rSV. Bronchiolitis was diagnosed in all hMPV-positive cases, while only two cases required hospitalization and supplemental oxygen therapy. our results provide further evidence of the importance of hMPV as a pathogen associated with community-acquired arTi in infants in Greece.

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“…La presentación de apneas durante el curso de una infección por MPVh ha sido descrita en 2 a 6% de los casos en algunas series, aumentando a 40% en el caso de prematuros, en quienes se describe el llamado complejo apnea-bradicardia [52][53][54] . La causa de esta forma de presentación aún no está establecida y pareciera ser de tipo obstructivo.…”

Section: Discussionunclassified

Apnea como forma de presentación de una infección por metapneumovirus humano

et al. 2007

Rev. chil. infectol.

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Apnea as a presenting symptom in human metapneumovirus infectionHuman metapneumovirus (hMPV), a recently described pathogen of lower respiratory tract infections (LRTI), has been detected in 5,4% of Chilean infants hospitalized for LRTI whom are negative for adenovirus, respiratory syncytial virus, influenza and parainfluenza viruses. hMPV may cause bronchiolitis or pneumonia in hospitalized patients, and ocassionally require admission to intensive care units and mechanical ventilation. The infection has been associated with apnea, especially in preterm infants. Nosocomial dissemination has also been described. We present the case of a one-month-of age premature infant with apnea, and infection caused by hMPV of probable nosocomial aquisition. Clinical features of hMPV infection are reviewed and its association with apnea and nosocomial transmission is discussed. hMPV should be included in the routine diagnosis of respiratory viruses in infants with apnea and should be considered among the respiratory pathogens associated with nosocomial transmission.

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Outbreak of Human Metapneumovirus Infection in Norwegian Children

Cited by 119 publications

References 13 publications

The Role of Human Metapneumovirus in Pediatric Respiratory Tract Infection in Qatar

The Role of Human Metapneumovirus in Pediatric Respiratory Tract Infection in Qatar

Detection of human metapneumovirus in infants with acute respiratory tract infection

Apnea como forma de presentación de una infección por metapneumovirus humano

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