Outbreak of hand, foot and mouth disease with onychomadesis caused by Coxsackie virus A16 in Granada

Moreno, Eduardo; López, David Ortega; Jiménez, R. Jaldo; Campana, Mara; Fernández, G; Ruiz, Mercedes Pérez; Nievas, Diego Almagro

doi:10.1016/j.anpede.2015.03.005

Anales de Pediatría (English Edition)

2015

DOI: 10.1016/j.anpede.2015.03.005

|View full text |Cite

Outbreak of hand, foot and mouth disease with onychomadesis caused by Coxsackie virus A16 in Granada

Eduardo Moreno

David Ortega López

R. Jaldo Jiménez³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2019

2021

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Onychomadesis and potential association with HFMD outbreak in a kindergarten in Hubei province, China, 2017

Xing

et al. 2019

BMC Infect Dis

View full text Add to dashboard Cite

BackgroundIn 2017, an outbreak of onychomadesis occurred in kindergarten H, Hubei province, China. We investigated the field to learn about the magnitude and reason of the outbreak.MethodsThe case definition was that a child with onychomadesis or transverse ridging (Beau’s line) in fingernails and toenails without previous traumatic or systemic disease in kindergarten H from Sep. 1st to Nov. 30th, 2017. A retrospective cohort study was carried out to analyze the epidemiological relationship between onychomadesis and the hand-foot-mouth disease (HFMD) in Primary Class #2, kindergarten H. We also performed a serological survey for neutralizing antibodies against coxsackie virus A6 (CVA6), coxsackie virus A10 (CVA10) among 15 cases and six healthy children in the kindergarten. Meanwhile, some children were carried out with routine blood, fungal microscopic and microelement tests. Indoor environment examinations had been done for all classes.ResultsA total of 20 cases were identified in Kindergarten H. Seventy-five percent (15/20) cases occurred in Primary Class #2. Fifty-five percent of the cases (11/20) had suffered from HFMD within two months. The median time between onychomadesis and HFMD was 45 days (ranging from 31 to 58 days). A retrospective cohort study in Primary Class #2 showed the attack rate was 90.0% among 10 children who suffered from HFMD in the past two months compared to 30.0% among 20 children who didn’t (Rate Ratio [RR] =3.0, 95% Confidence Interval [CI] =1.5–6.0). The positive rates of neutralizing antibodies were 66.7% for CVA6 and 26.7% for CVA10 in tested cases. The result of routine blood, fungal microscopic, microelements tests were normal in cases. The indicators of environment were within the normal range.ConclusionThe results of this study suggested that the outbreak of onychomadesis in Hubei province was probably associated with HFMD epidemic within two months.

show abstract

Onychomadesis and potential association with HFMD outbreak in a kindergarten in Hubei province, China, 2017

Xing

et al. 2019

BMC Infect Dis

View full text Add to dashboard Cite

show abstract

Epidemiological characteristics of outbreaks of hand, foot and mouth disease in kindergartens in Belgrade during the period from 2015 to 2019

Giljača¹,

Maris²,

Rančić³

et al. 2021

Zdravstvena zaštita

View full text Add to dashboard Cite

Introduction/Aim: For the first time in the world Hand, Foot and Mouth Disease was reported in 1957 in Canada, while the first outbreak of this disease was registered in Belgrade in 2014.The aim of this paper is to analyze epidemiological characteristics of outbreaks of HFMD, which occurred in kindergartens in Belgrade in the period from 2015 to 2019. Methods: A descriptive epidemiological study was applied. Data were collected from epidemiological questionnaires, Reports of Center for Disease Control and Prevention, City Institute of Public Health Belgrade, from the case history of sick children, and using the results of the virological and serological analyses that had been done in the Reference Laboratory of the Institute of Virology, Vaccines, and Sera "Torlak". Results: In the period from 2015 to 2019, 20 HFMD outbreaks were registered, in which a total of 220 children became ill. The total number of infected children in outbreaks ranged from 9 to 102. Boys were slightly more often ill (52%), as well as persons aged two years (51%). All patients had a maculopapular rash, and most had a fever (96%) and malaise (68%). Enterovirus was detected by Real-Time PCR in two infected children. The disease passed without any complications. Conclusion: By timely application of anti-epidemic measures, by reporting the disease, isolation and treatment of patients, respecting the measures of general and personal hygiene, as well as measures of current disinfection in the collective, it is possible to successfully stop further spread of the infection.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Outbreak of hand, foot and mouth disease with onychomadesis caused by Coxsackie virus A16 in Granada

Cited by 2 publications

References 16 publications

Onychomadesis and potential association with HFMD outbreak in a kindergarten in Hubei province, China, 2017

Onychomadesis and potential association with HFMD outbreak in a kindergarten in Hubei province, China, 2017

Epidemiological characteristics of outbreaks of hand, foot and mouth disease in kindergartens in Belgrade during the period from 2015 to 2019

Contact Info

Product

Resources

About