Outbreak of Burkholderia cepacia Bacteremia Caused by Contaminated Chlorhexidine in a Hemodialysis Unit

Romero-Gómez, María Pilar; Quiles-Melero, M. I.; García, P. Peña; Altés, A. Gutiérrez; Miguel, M.aJ. García de; Jiménez, C; Valdezate, Sylvia; Nieto, Juan Antonio

doi:10.1086/529032

Cited by 43 publications

(25 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…342,343 Many healthcareassociated outbreaks of Burkholderia infections associated with contaminated skin antiseptics, mouthwashes, ultrasound gels, medications, and medical devices have been described. [344][345][346][347][348][349][350][351][352][353][354][355][356][357][358][359][360][361][362] Other products that have become contaminated during use include nasal irrigation bottles contaminated with P. aeruginosa, 363,364 multiuse albuterol vials contaminated with B. cepacia, 348,357 acupuncture devices disinfected with glutaraldehyde contaminated with M. abscessus, 365 cosmetic surgical supplies contaminated with mycobacterial spp., and supplies used for liposuction. 366 Outbreaks of Achromobacter spp.…”

Section: Iiid2 Healthcare Sources: Water Surfaces Equipment Airmentioning

confidence: 99%

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Saiman

Siegel

LiPuma

et al. 2014

Infect. Control Hosp. Epidemiol.

344

382

View full text Add to dashboard Cite

The 2013 Infection Prevention and Control (IP&C) Guideline for Cystic Fibrosis (CF) was commissioned by the CF Foundation as an update of the 2003 Infection Control Guideline for CF. During the past decade, new knowledge and new challenges provided the following rationale to develop updated IP&C strategies for this unique population:1. The need to integrate relevant recommendations from evidence-based guidelines published since 2003 into IP&C practices for CF. These included guidelines from the Centers for Disease Control and Prevention (CDC)/Healthcare Infection Control Practices Advisory Committee (HICPAC), the World Health Organization (WHO), and key professional societies, including the Infectious Diseases Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA). During the past decade, new evidence has led to a renewed emphasis on source containment of potential pathogens and the role played by the contaminated healthcare environment in the transmission of infectious agents. Furthermore, an increased understanding of the importance of the application of implementation science, monitoring adherence, and feedback principles has been shown to increase the effectiveness of IP&C guideline recommendations.2. Experience with emerging pathogens in the non-CF population has expanded our understanding of droplet transmission of respiratory pathogens and can inform IP&C strategies for CF. These pathogens include severe acute respiratory syndrome coronavirus and the 2009 influenza A H1N1. Lessons learned about preventing transmission of methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant gram-negative pathogens in non-CF patient populations also can inform IP&C strategies for CF.

show abstract

Section: Iiid2 Healthcare Sources: Water Surfaces Equipment Airmentioning

confidence: 99%

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Saiman

Siegel

LiPuma

et al. 2014

Infect. Control Hosp. Epidemiol.

344

382

View full text Add to dashboard Cite

show abstract

“…A review of FDA product recalls (1998 to 2006) reported B. cepacia as the most frequently isolated Gramnegative contaminant of sterile and nonsterile pharmaceuticals (3). Outbreaks of Bcc infection in vulnerable individuals have resulted from the use of contaminated antimicrobial/preserved industrial products (7)(8)(9)(10). Burkholderia contaminans (11) was given its systematic species name because of its linkage to a globally distributed strain associated with multiple incidents of contamination and opportunistic infection (12).…”

mentioning

confidence: 99%

Key Role for Efflux in the Preservative Susceptibility and Adaptive Resistance of Burkholderia cepacia Complex Bacteria

Rushton

Saß

Baldwin

et al. 2013

Antimicrob Agents Chemother

View full text Add to dashboard Cite

“…Questi microorganismi però sono anche in grado di causare infezioni nosocomiali in pazienti immunocompromessi, grazie alla loro capacità di colonizzare forniture di acqua, disinfettanti e strumenti utilizzati per la dialisi (3,4,5). Una volta instaurata, l'infezione risulta difficile da eradicare, poiché il batterio è intrinsecamente resistente a numerosi antibiotici.…”

Section: Introduzioneunclassified