Our Experience With Wet-Wrap Treatment

Albarrán-Planelles, C.; Jiménez‐Gallo, David; Linares‐Barrios, Mario; Martínez-Rodríguez, A.

doi:10.1016/j.adengl.2013.11.003

Cited by 4 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reviewing the literature on side effects in WWT leads to a division into 3 categories (Table II): expected discomforts regarding the use of moist bandages (8,10,23,36), skin infections and probably the most serious adverse effect: possible systemic bioactivity of the TCS. Infections.…”

Section: What Are Potential Adverse Effects?mentioning

confidence: 99%

The Role of Wet Wrap Therapy in Skin Disorders – A Literature Review

Andersen¹,

Thyssen²,

Maibach³

2015

Acta Derm Venerol

View full text Add to dashboard Cite

Wet wrap therapy, based on skin application of a double layer of tubular bandages or gauze with a moist first inner layer and a dry second outer layer, is utilized to treat various pruritic conditions, in particular severe and refractory atopic dermatitis. This review, by literature search, evaluates current knowledge about wet wrap therapy. Wet wrap therapy superimposed topical corticosteroids appears more efficient than emollients only, at least for short-time treatments. Despite higher efficacy, there is a tendency towards more frequent infections when topical corticosteroids are covered with wet wrap bandages compared to emollients only. While temporary suppression of hypothalamic-pituitary-adrenocortical-axis was seen due to systemic bioactivity of corticosteroids, no long-term observation studies on putative adverse effects were identified. One hypothesis suggests that wet wrap therapy may trigger increased lamellar body secretion resulting in recovery of the damaged intercellular lipid laminar structure. Otherwise, little investigation on mechanisms exists.

show abstract

Section: What Are Potential Adverse Effects?mentioning

confidence: 99%

The Role of Wet Wrap Therapy in Skin Disorders – A Literature Review

Andersen¹,

Thyssen²,

Maibach³

2015

Acta Derm Venerol

View full text Add to dashboard Cite

show abstract

“…Wet-wrap therapy (WWT) can be helpful to quickly reduce AD severity, and it is often useful for acute flares and/or recalcitrant disease 88 89 90 91 92 93 94 95 96 97 . For better results and to reduce the risk of infection, WWT use must be based on proper education and can be administered on an outpatient or inpatient basis 88 94 .…”

Section: Resultsmentioning

confidence: 99%

Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment

Kim

Lew

et al. 2015

Ann Dermatol

View full text Add to dashboard Cite

BackgroundSince the treatment guidelines for atopic dermatitis (AD) were released by the Korean Atopic Dermatitis Association (KADA) work group in 2006, there have been several advances in AD management.ObjectiveWe aimed to establish updated evidence- and experience-based treatment guidelines for Korean AD.MethodsWe collected a database of references from relevant systematic AD reviews and guidelines regarding general AD management such as bathing and skin care, avoidance of exacerbating factors, education and psychosocial support, and the use of moisturizers and topical anti-inflammatory and antipruritic drugs. Evidence for each statement was graded and the strength of the recommendation for each statement classified. Thirty-nine KADA council members participated in three rounds of voting to establish an expert consensus of recommendations.ResultsBasic AD treatment includes proper bathing and skin care, avoidance of exacerbating factors, proper education and psychosocial support, and use of moisturizers. The regular use of moisturizer has a steroid-sparing effect and reduces relapse episodes. The short- and long-term use of topical corticosteroids and calcineurin inhibitors improves AD symptoms and should be encouraged to use in an active and proactive treatment. Wet-wrap therapy can be used for rapid recovery of acute exacerbation. Topical antipruritic drugs cannot be recommended for the treatment of AD.ConclusionThis report provides up-to-date evidence- and experience-based treatment guidelines for AD regarding general management and topical treatment. In addition, the average agreement scores obtained by a panel of experts based on the Korean healthcare system and patient adherence are presented.

show abstract

“…3,4 WWT is an interesting alternative for short-term control in patients with severe or refractory flares that avoids the use of systemic and potentially more toxic treatments. 3,4 Its efficacy has been claimed to derive from better penetration of the steroid, decrease in transepidermal water loss, or from the wraps acting as a barrier against scratching. 3 Several studies and qualitative reviews on WWT have reported promising results in the management of AD, although the number of patients included has been small.…”

Section: What Does This Study Add?mentioning

confidence: 99%

“…Wet wrap therapy (WWT) involves the application of a topical steroid, diluted or not, under two layers of cotton bandages or garments: a wet inner layer and a dry outer layer. Wraps are left for 8–24 h per day, and treatment duration should not exceed 14 days . WWT is an interesting alternative for short‐term control in patients with severe or refractory flares that avoids the use of systemic and potentially more toxic treatments .…”

mentioning

confidence: 99%

“…Wraps are left for 8–24 h per day, and treatment duration should not exceed 14 days . WWT is an interesting alternative for short‐term control in patients with severe or refractory flares that avoids the use of systemic and potentially more toxic treatments . Its efficacy has been claimed to derive from better penetration of the steroid, decrease in transepidermal water loss, or from the wraps acting as a barrier against scratching .…”

mentioning

confidence: 99%

See 1 more Smart Citation

Efficacy and safety of wet wrap therapy for patients with atopic dermatitis: a systematic review and meta‐analysis

et al. 2017

View full text Add to dashboard Cite

Wet wrap therapy (WWT) consists of topical steroids administered under a layer of wet cotton bandages or garments. Several trials with WWT have reported promising results in atopic dermatitis (AD). However, no systematic review and meta-analysis on its efficacy and safety has been published. Our objective was to conduct a systematic review of the literature on WWT in AD to assess its efficacy and safety. We included randomized controlled trials among patients of all ages with a diagnosis of AD based on predefined criteria or made by a dermatologist. Electronic searches were performed from 1970 to 30 March 2016 in the Cochrane Central Register of Controlled Trials, MEDLINE, Embase and the World Health Organization International Clinical Trials Registry. Selection of studies and data extraction were performed independently by two researchers, and discrepancies were resolved by consensus. Six trials comparing WWT with topical steroids in children or adults with AD were included. Sample sizes ranged from 19 to 51 patients. Results on clinical severity and quality of life were reported incompletely and proved heterogeneous across studies. A nonsignificant tendency to increased risk of mild skin infections was observed in those treated with WWT (pooled relative risk 6·35, 95% confidence interval 0·83-48·55). The overall grade of quality of evidence for the efficacy and safety outcomes was low. In conclusion, the evidence that WWT is more effective than conventional treatment with topical steroids in AD is of low quality. Further clinical trials should establish the efficacy of WWT in AD.

show abstract

Our Experience With Wet-Wrap Treatment

Cited by 4 publications

References 8 publications

The Role of Wet Wrap Therapy in Skin Disorders – A Literature Review

The Role of Wet Wrap Therapy in Skin Disorders – A Literature Review

Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment

Efficacy and safety of wet wrap therapy for patients with atopic dermatitis: a systematic review and meta‐analysis

Contact Info

Product

Resources

About