Our experience in the management of infantile hydrocephalus: A study on thirty-five regrouped cases in Yaounde, Cameroon

Tambo, FF Mouafo; Djientcheu, Vincent de Paul; Chiabi, Andréas; Mbarnjuk, SA; Walburga, YJ; Mbonda, Elie; Sosso, MA

doi:10.4103/0189-6725.86062

Cited by 13 publications

(4 citation statements)

References 7 publications

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“…HC secondary to post-intraventricular hemorrhage was the least common cause of HC requiring a shunt in infancy. All these trends are consistent with previous studies such as those by Mouafo Tambo et al ,[ 10 ] in which they found aqueductal stenosis in 31.43% cases.…”

Section: Discussionsupporting

confidence: 93%

Study of Neurodevelopmental Outcome in Patients with Non-tumoral Hydrocephalus with Shunt Surgery Done in Infancy

et al. 2021

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A BSTRACT Background: Hydrocephalus (HC) is a common neurological disorder presenting in infancy, with a myriad of etiologies requiring early neurosurgical intervention. Objective: To study neurodevelopmental outcome in patients with HC with shunt surgery done in infancy. Materials and Methods: This was an observational retrospective cohort study of 50 pediatric patients (2 years to 16 years of age). These patients were diagnosed with HC and were operated on with ventriculo-peritoneal shunt (VP shunt) insertion in infancy (did not include patients with brain tumors) and then later following in the neurology outpatient department (OPD). Clinical records and neurodevelopmental assessment (intelligence quotient [IQ]/development quotient [DQ] and vision and hearing assessment) were reviewed. Results: Only 50% of the patients with congenital HC were diagnosed at birth, which included patients who had been diagnosed antenatally and they had lesser complications and better intellectual outcome ( P = 0.12), compared with those who presented later with HC. Patient-related factors such as etiology of HC, antenatal diagnosis, and requirement of shunt revisions had poor correlation with neurodevelopmental outcome. Patients with late postoperative complications had significantly poor neurodevelopmental outcome ( P ≤ 0.001). Patients with post-meningitis HC required a significantly higher number of shunt revisions than patients with other causes ( P = 0.04). Conclusion: Better neurodevelopmental outcome depends on early diagnosis and early referral for the management than the cause of HC. Regular head circumference monitoring is the most feasible and sensitive screening tool for early pickup. Larger studies are needed for accurate prognostication.

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Section: Discussionsupporting

confidence: 93%

Study of Neurodevelopmental Outcome in Patients with Non-tumoral Hydrocephalus with Shunt Surgery Done in Infancy

et al. 2021

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“…Les taux de complications varient entre 1 et 50%, deux ans après la chirurgie [ 2 , 12 , 22 - 25 ]. Dans les séries de l´Afrique subsaharienne, les complications décrites varient entre 7% et 69% et sont liées à des causes mécaniques (11-54%) et à l´infection (7-69%) [ 6 , 13 , 23 , 24 , 26 - 28 ]. La pose de DVP est plus dangereuse dans le contexte africain que dans les pays développés en raison des complications infectieuses et du dysfonctionnement de valve [ 25 ].…”

Section: Discussionunclassified

Hydrocéphalie du nouveau-né et du nourrisson au Centre Hospitalier National de Nouakchott

Salem-Memou¹,

Chavey²,

Elmoustapha³

et al. 2020

Pan Afr Med J

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L´hydrocéphalie du nouveau-né et du nourrisson constitue un facteur important de mortalité et de morbidité dans les pays en voie de développement avec des moyens diagnostiques et thérapeutiques limités. Cette étude avait pour objectif de rapporter notre expérience dans la prise en charge de cette pathologie en Mauritanie. Il s´agissait d´une étude rétrospective portant sur 126 dossiers d´enfants d´âge compris entre 0 et 24 mois, pris en charge pour hydrocéphalie dans le service de neurochirurgie du CHN de Nouakchott, de juin 2014 au juin 2018. Le délai moyen de suivi était de 15 mois (9-27 mois). L´âge moyen au diagnostic était de 5 mois (2 jours à 20 mois). On notait une prédominance féminine (sex-ratio de 0,77). La série était composée de 45 nouveau-nés (35,7%) et de 81 nourrissons (64,3%). Un antécédent infectieux de la grossesse avait été retrouvé dans 19,8% et une infection néonatale dans 23,8%. Sur le plan clinique, 87,3% avaient une macrocéphalie, 35,7% un retard du développement psychomoteur et 15,8% un refus de téter. La principale étiologie était représentée par les myéloméningoceles (23,8%), suivie de la méningite (15,8%). La dérivation ventriculo-péritonéale (DVP) était le principal traitement chez le nouveau-né (68,8%), tandis que la ventriculocisternostomie endoscopique (VCE) était préférée chez le nourrisson (74,1%). Le taux global de complications était de 26,1% (57,6% pour les DVP et 4,1% pour la VCE). L´hydrocéphalie est la principale pathologie de la neurochirurgie pédiatrique en Afrique. Sa prise en charge reste tardive, d´où l´importance de la prévention surtout des anomalies du tube neural et des infections.

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“…In the series of sub-Saharan Africa, the described complications vary between 7% and 69% and are related to mechanical causes (obstruction and VPS system migration) (11-54%) and infection (7-69%). [ 4 28 31 35 37 39 40 44 ] Even when the VPS placement is possible, it is more dangerous in the African context than in developed countries because of the infectious complications and shunt's malfunctioning. [ 42 ] Infectious complications of VPS implantation can be reduced by implementing protocols that train staff in infection control measures related to the preoperative, operative, and postoperative period, as reported by Choux et al .,[ 6 ] being fundamental to adapt this knowledge to local reality.…”

Section: Discussionmentioning

confidence: 99%

“…A large number of children may alternatively benefit from endoscopic third ventriculostomy (ETV), which is a treatment option, without heterologous material, with a long-term lower rate of associated complications[ 17 23 39 43 ] and with a follow-up that we believe can be less frequent, thus reducing the socioeconomic impact on the families of these patients. [ 46 47 ]…”

Section: Discussionmentioning

confidence: 99%

Hydrocephalus in children less than 1 year of age in northern Mozambique

et al. 2014

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Background:In developed countries, the incidence of neonatal hydrocephalus ranges from 3 to 5 cases per 1000 live births, but little is known about the frequency of hydrocephalus in Africa. In Mozambique, there is no primary information related to this disorder, but using the above data, the expected incidence of neonatal hydrocephalus would range from 2900 to 4800 cases per year.Methods:This study is based on 122 children younger than 1 year with neonatal hydrocephalus, followed up between January 2010 and December 2012, their origin and treatment, and aims to evaluate difficulties with diagnosis, treatment, and follow-up in northern Mozambique.Results:Identified cases were mainly less than 6 months old (77%), with severe macrocephaly and the classic stigmata of this condition. A high rate of follow-up loss (44.3%) was detected, particularly among children from more distant locations. Our findings contrast with the expected 1000-1700 cases that would occur in the area during the study period, being considerably lower.Conclusions:Hydrocephalus is a serious problem in sub-Saharan Africa, whose effects can be minimized by a better organization of the health system in hydrocephalus prevention, referral, and follow-up. New management alternatives to provide treatment to more children with this disorder and reduction of the follow-up difficulties caused due to geographical reasons for the children undergoing treatment are essential.

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Our experience in the management of infantile hydrocephalus: A study on thirty-five regrouped cases in Yaounde, Cameroon

Cited by 13 publications

References 7 publications

Study of Neurodevelopmental Outcome in Patients with Non-tumoral Hydrocephalus with Shunt Surgery Done in Infancy

Study of Neurodevelopmental Outcome in Patients with Non-tumoral Hydrocephalus with Shunt Surgery Done in Infancy

Hydrocéphalie du nouveau-né et du nourrisson au Centre Hospitalier National de Nouakchott

Hydrocephalus in children less than 1 year of age in northern Mozambique

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