Otto Loewi: One Hundred Years of Confirmation of Chemical Neurotransmission

Abstract

In 1921, Otto Loewi published an experimental study that gave rise to the birth of the chemical theory of nerve transmission, according to which, the nerve current causes, at the end of nerve fibers, the release of a chemical substance called a neurotransmitter. For his discoveries related to the chemical neurotransmission of nerve impulses, Loewi received the Nobel Prize in Physiology or Medicine in 1936.