Ototoxicity

Gotthelf, Louis N.

doi:10.1016/b0-72-160137-5/50020-9

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…A variety of drugs and other chemicals have been demonstrated to have toxic effects on the inner ear, affecting auditory and / or vestibular function. 78-83 The most prominent of these are the aminoglycoside antibiotics, 84-88 antineoplastic agents, 89 diuretics and antiseptics.…”

Section: Acquired Deafnessmentioning

confidence: 99%

Hearing disorders in cats: Classification, pathology and diagnosis

Strain

2017

Journal of Feline Medicine and Surgery

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Practical relevance: Auditory function is a sense that is central to life for cats - being important in situational awareness of potential predators, pursuit of prey, and for communication with conspecifics, humans and other species. Deafness in cats is most frequently the result of a genetic disorder, strongly associated with white fur and blue eyes, but may also result from acquired causes such as advancing age, ototoxic drugs, infection, environmental noise and physical trauma. Deafness can be sensorineural, where there is loss of cochlear hair cells, or conductive, where sound is muffled on its way to the inner ear. Clinical challenges: Establishing whether a cat is deaf can be difficult as behavioral testing of hearing is subjective and does not reliably detect unilateral deafness. Brainstem auditory evoked response testing is an objective measure but is limited in its availability. Currently, sensorineural deafness is irreversible because no treatments are available to restore lost hair cells. Conductive hearing loss can usually be treated, although full hearing recovery following otitis media may take weeks as the body clears the middle ear of debris. Evidence base: The author draws on the published literature and his extensive research on clinical aspects and molecular genetics of deafness, principally in companion animals, to review types and forms of deafness in cats. He also discusses current diagnostic approaches and provides brief advice for managing cats with hearing loss.

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Section: Acquired Deafnessmentioning

confidence: 99%

Hearing disorders in cats: Classification, pathology and diagnosis

Strain

2017

Journal of Feline Medicine and Surgery

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“…São ácaros com alto potencial de contágio e a transmissão acontece por contato direto. Os mesmos, predispõem ao aparecimento no animal, otohematomas, que normalmente estão ligados ao prurido, hiperemia e exsudação dura e escura formada pela irritação das glândulas ceruminosas, podendo acarretar casos de hipersensibilidade, podendo variar de apresentação devido a infecção secundária bacteriana, fúngica ou ambas (GOTTHELF, 2000;ROSSER, 2004;SOUZA, 2015).…”

Section: Introductionunclassified

Testes de controle de qualidade realizados em comprimidos de hidroclorotiazida provenientes do Programa Farmácia Solidária de Maringá (PR)

González¹,

Freire²,

Bonassoli³

et al. 2023

Anais Do I Congresso Internacional Interdisciplinar Da Uningá: Resumos Expandidos

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O programa ‘Farmácia Solidária’ foi implementado em Maringá (PR) no ano de 2019, com objetivo de receber fármacos doados pela população e redistribuí-los por meio das UBS para quem necessite. O presente trabalho teve como objetivo avaliar por meio de testes físico-químicos oficiais, a qualidade de alguns comprimidos distribuídos no programa Farmácia Solidária. Foram analisados comprimidos gené ricos de hidroclorotiazida 25mg e comparados com a referência Clorana® 25mg, este adquirido em far mácia comercial de Maringá. Os testes realizados foram peso médio, dureza, friabilidade, desintegração, dissolução e doseamento. Os comprimidos testados apresentam valores dentro dos parâmetros descritos na Farmacopeia Brasileira 6.a edição.

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References

2012

Canine and Feline Dermatology Drug Handbook

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Ototoxicity

Cited by 3 publications

References 16 publications

Hearing disorders in cats: Classification, pathology and diagnosis

Hearing disorders in cats: Classification, pathology and diagnosis

Testes de controle de qualidade realizados em comprimidos de hidroclorotiazida provenientes do Programa Farmácia Solidária de Maringá (PR)

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