Otological findings among Nigerian children with sickle cell anaemia

Alabi, Stephen Adeyemi; Ernest, Kolade; Eletta, Paul Adebisi; Owolabi, Adesina; Afolabi, A.A.; Suleiman, O A

doi:10.1016/j.ijporl.2008.01.024

Cited by 30 publications

(53 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They have stated that CHL was caused by otitis media with effusion. But the rate of CHL is low [14,15].…”

Section: Discussionmentioning

confidence: 98%

“…Taipale et al [4]'s showed that there was a bilateral hearing loss of 36%, Alabi et al [15] 13.4%, while Mgbor determined it as 6% and Tsibuleyskaya et al [21] determined it as 12.5% in SCA patients. Silva et al [22] have reported in their study in which they included 80 patients with SCA that 33 of the patients had bilateral hearing loss [4,8,15,21].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of Hearing and Balance Functions of Patients with Sickle Cell Anemia

2018

View full text Add to dashboard Cite

Introduction: Sickle cell anemia is a disease characterized by a wide vaso-occlusive incident from micro-vascular incident to muscularactivity. The cochlear function can also get affected by this vaso-occlusion. Objective: It is aimed at determining what kind of effects sickle cell anemia has on hearing and balance system. Methods: This study has been conducted on 46 patients with sickle cell anemia and 45 healthy individuals. For all participants, their pure tone hearing thresholds and videonystagmography (VNG) findings have been determined in 17 frequencies between 125–16.000 Hz. Results: All hearing thresholds between 125 and 16,000 Hz, pure tone averages of patients with sickle cell anemia have been found statistically significant to be higher than the corresponding values in the control group(p < 0.05). The normal hearing rate of patients with sickle cell anemia has been determined to be 71.1% conductive hearing loss (CHL) to be 4.4%, sensorineural hearing loss (SNHL) to be 22.2%, and mixed type hearing loss to be 2.2% in right ear; the normal hearing rate has been determined to be 71.1%, CHL to be 2.2%, SNHL to be 22.2%, and mixed type hearing loss to be 4.4% in left ear. Statistically significant difference has not been found between head shake, spontaneous nystagmus, optokinetic, tracking test batteries, static and dynamic positional tests used in VNG, saccade accuracy and saccade peak velocity, which are saccadic test findings of 2 groups. However, saccadic latency, which is a saccadic test finding, has been determined to be longer in patients with sickle cell anemia in comparison to the control group. Conclusion: While sickle cell anemia causes hearing deficits, it does not have any effect on the central or peripheral vestibular system.

show abstract

“…They have stated that CHL was caused by otitis media with effusion. But the rate of CHL is low [14,15].…”

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Evaluation of Hearing and Balance Functions of Patients with Sickle Cell Anemia

2018

View full text Add to dashboard Cite

show abstract

“…Queries were stratified by age and sex. The cohort excluded those with sickle cell disease (282.6 and D57) due to previous studies linking sickle cell anemia with hearing loss (Alabi et al, 2008;Koussi et al, 2001;Mgbor & Emodi, 2004;Odetoyinbo & Adekile, 1987;Saito et al, 2011;Samperi et al, 2005;Taipale et al, 2012).…”

Section: Study Populationmentioning

confidence: 99%

“…As the epidemiology of hearing loss varies by age, sudden SNHL is less common in the pediatric population (J. H. Chung, Cho, Jeong, Park, & Lee, 2015). Some studies have linked SNHL to sickle cell anemia in pediatrics (Alabi et al, 2008;Koussi et al, 2001;Mgbor & Emodi, 2004;Odetoyinbo & Adekile, 1987;Saito et al, 2011;Samperi, Bertuna, Rossi, Poli, & Serra, 2005;Taipale, Pelkonen, Bernardino, Peltola, & Pitkaranta, 2012) with the proposed mechanism of this relationship being the occlusion of the blood vessels by the sickled red cells, resulting in ischemia (Ondzotto et al, 2002). However, this mechanism would not be applicable to individuals with IDA because sickle cell anemia patients have normal levels of iron, and the sickle cell shape is only characteristic of those with sickle cell anemia.…”

mentioning

confidence: 99%

The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population

et al. 2017

View full text Add to dashboard Cite

Purpose A correlation between iron deficiency anemia (IDA) and sudden sensorineural hearing loss (SNHL) was described in adults. In this study, we examined if there is a relationship between IDA and hearing loss in the pediatric population. Method This was a retrospective cohort study of data collected from the Informatics for Integrating Biology and the Bedside database from 2011 to 2016. Children and adolescents 4–21 years old seen at Penn State Milton S. Hershey Medical Center, Hershey, PA, were examined for hearing loss and IDA status. Hearing loss was determined by International Classification of Disease-9 and -10 codes, and IDA was determined by both low hemoglobin and serum ferritin levels for age and sex. Results We identified 20,113 patients. Prevalence of hearing loss and IDA was 1.7% and 2.3%, respectively. The prevalence of all hearing loss was 3.0% in the IDA cohort and 1.7% in those without IDA. Children and adolescents with IDA are at increased odds of developing SNHL (adjusted odds ratio: 3.67, 95% CI [1.60–7.30]). Conclusions Children with IDA demonstrate increased likelihood of SNHL. Although correction of IDA in those with hearing loss has yet to be linked to improvements in hearing outcomes, screening for and correcting IDA among pediatric patients will positively affect overall health status. Supplemental Material: https://doi.org/10.23641/asha.5087071

show abstract

“…3 SNHL is a well-recognized complication of SCD. [4][5][6][7][8][9][10][11] LH and LO have been reported to affect the inner ear in SCD; however, the association between inner ear involvement and imaging findings has not been fully described. Our purpose was to examine the prevalence of inner ear involvement of LH and LO and to assess the relationship between clinical and imaging findings of LH and LO in SCD.…”

mentioning

confidence: 99%