Otolaryngology-Specific Symptoms May Be Highly Observed in Patients With a History of Covid-19 Infection After Inactivated Coronavirus Vaccination

Abstract

Objective: To evaluate the otolaryngology-specific symptoms that occur after receiving the Covid-19 vaccine and its possible side effects in patients who had Covid-19 infection in the last 6 months before the vaccination. Patients and Methods: The study comprised 3383 health care workers who were vaccinated against Covid 19. After excluding, the study was conducted with 1710 (51%) participants who agreed to answer the study questions. The participants were divided into 2 groups according to the history of Covid-19 positivity in the last 6 months before vaccination. The presence of symptoms related to otolaryngology practice, including cough, nasal congestion, rhinorrhea, sore throat, hearing loss, dizziness, loss of smell, loss of taste, ear pressure, and facial paralysis was recorded. Results: The mean age of the study population was 35.79 ± 10.2 (19-71) years and 1454 (85%) of the patients had a history of Covid-19 infection in the last 6 months. Regarding otolaryngology-related symptoms, the most common complaints were rhinorrhea (4.4%), sore throat (3.2%), and nasal congestion (2.9%). The presence of smell and taste loss, nasal congestion, rhinorrhea, sore throat, and hearing loss was significantly more common in patients with a history of Covid-19 infection. Conclusions: The patients with a history of Covid-19 disease might have otolaryngology-specific symptoms more commonly than those without a history of Covid-19 disease in the last 6 months before vaccination.

Do the Successive Waves of SARS-CoV-2, Vaccination Status and Place of Infection Influence the Clinical Picture and COVID-19 Severity among Patients with Persistent Clinical Symptoms? The Retrospective Study of Patients from the STOP-COVID Registry of the PoLoCOV-Study

“…For example, the observation by Vaira, L. et al, shows that vaccination does not reduce the incidence of these symptoms [ 32 ]. Avci, H. et al, made similar observations [ 33 ]. These data are inconsistent with our results, which, combined with the small amount of data, indicates the need for further exploration of the topic, especially since these symptoms are one of the most characteristics of COVID-19 [ 6 ].…”

Acute Vertigo After COVID-19 Vaccination: Case Series and Literature Review

“…In a large study on 3,383 healthcare workers who received the inactivated COVID-19 vaccine (CoronaVac, Sinovac Life Sciences). Otolaryngology-specific symptoms were showed as significantly more common in subjects with a history of COVID-19 infection ( 16 ). Differently from us, in this case the authors paid attention to the previous infection and postulated that vaccination may play a triggering role in the activation of symptoms in patients with the previous COVID-19 infection.…”

Sensorineural Hearing Loss Post-COVID-19 Infection: An Update

“…Finally, since December 2020, as the European Medicines Agency (EMA) approved the first vaccine against COVID-19 (Pfizer-BioNTech), a large immunization campaign commenced and potential vaccine-related adverse effects, including audio-vestibular effects, were reported. Few case reports and small sample studies suggested a possible link between vaccination and an increased risk of SNHL, however with a very low level of evidence [ 36 , 37 , 38 , 39 , 40 , 41 , 42 ]. Even if a clear and defined relationship between the COVID-19 vaccination and SSNH cannot be identified in the literature to date, we expect that further studies and reports on this topic could be available in the future.…”