Otitis Media Following Tympanostomy Tube Placement in Children With IgG<sub>2</sub> Deficiency

Masin, Jeffrey S.; Hostoffer, Robert; Arnold, James E.

doi:10.1288/00005537-199511000-00009

Cited by 8 publications

(5 citation statements)

References 7 publications

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“…It is believed that these infections are secondary to impaired antibody response, rather than Eustachian tube dysfunction [13]. As immunological derangements seem to be common in TS, an immunological deficiency could be a potential cause to parts of the ear problems.…”

Section: Introductionmentioning

confidence: 99%

Immunological parameters in girls with Turner syndrome

Stenberg

Sylvén

Magnusson³

et al. 2004

J Negat Results BioMed

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Disturbances in the immune system has been described in Turner syndrome, with an association to low levels of IgG and IgM and decreased levels of T-and B-lymphocytes. Also different autoimmune diseases have been connected to Turner syndrome (45, X), thyroiditis being the most common.Besides the typical features of Turner syndrome (short stature, failure to enter puberty spontaneously and infertility due to ovarian insufficiency) ear problems are common (recurrent otitis media and progressive sensorineural hearing disorder).Levels of IgG, IgA, IgM, IgD and the four IgG subclasses as well as T-and B-lymphocyte subpopulations were investigated in 15 girls with Turners syndrome to examine whether an immunodeficiency may be the cause of their high incidence of otitis media. No major immunological deficiency was found that could explain the increased incidence of otitis media in the young Turner girls.

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Section: Introductionmentioning

confidence: 99%

Immunological parameters in girls with Turner syndrome

Stenberg

Sylvén

Magnusson³

et al. 2004

J Negat Results BioMed

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“…The time between the additional codes and the index procedure for TT placement was recorded. The following ICD‐9‐CM codes were used to exclude individuals from the study: 744.x (congenital abnormalities), 279.x (immunodeficiency disorders), 277.0x (cystic fibrosis), 759.3 (Kartagener syndrome), 749.0 to 749.24 (cleft palate), and 758 (Down's syndrome), as these patients are more likely than the general population to require tympanostomy tubes, which could have skewed our data for need of repeated tube placement 9‐12 . In addition, removal of a foreign object was also excluded ( CPT codes 69200 and 69210) because these codes are not exclusively for tube removal.…”

Section: Methodsmentioning

confidence: 99%

Sequelae of Tympanostomy Tubes in a Multihospital Health System

Padia

Hall

Sjogren

et al. 2018

Otolaryngol.--head neck surg.

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Objectives Review the incidence of long-term sequelae after placement of tympanostomy tubes. Study Design Case series with chart review. Setting Multihospital network. Subjects Patients 0 to 3 years old undergoing tympanostomy tube (TT) placement. Methods A case series of 14,058 children between 2004 and 2010 was reviewed. The patients were followed for 5 years to determine number of repeated tube placements, need for surgical removal of tubes, and presence of perforation requiring repair. Results The study cohort included 14,058 children who underwent TT placement. The mean age at time of procedure was 1.4 years. A total of 14.4% of patients required a second set of tubes within the 5 years of follow-up studied, and 4.6% required 3 or more sets. Three percent required removal of a tube, and this occurred at an average time of 34.2 ± 17.6 months postplacement. In total, 5.1% had a resulting perforation after either tube extrusion or tube removal requiring myringoplasty. Conclusions The rate of multiple tube placements and myringoplasty and tympanoplasty to correct resulting perforations has yet to be studied in a single large population. This information allows for more detailed preoperative counseling to patients and families. Better characterization of these populations with accurate rates of sequelae can help to tailor treatment and preoperative counseling in the future.

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“…The following ICD‐9‐CM codes were used to exclude individuals from the study: 744.x (congenital abnormalities), 279.x (immunodeficiency disorders), 277.0x (cystic fibrosis), 759.3 (Kartagener syndrome), 749.0‐749.24 (cleft palate), and 758 (Down syndrome), as these patients are more likely than the general population to require tympanostomy tubes . These predisposing conditions used to exclude case subjects were also applied to the control population.…”

Section: Methodsmentioning

confidence: 99%