Otitis Media and Facial Paralysis as Presenting Symptoms of a Primary Middle Ear Sarcoidosis

Arsović, Nenad; Babić, Borivoj; Dimitrijević, Mirjana; Bukurov, Bojana; Vučinić, Violeta

doi:10.1097/mao.0b013e3182a09b21

Cited by 2 publications

(3 citation statements)

References 2 publications

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“…Audiovestibular symptoms of sarcoidosis are uncommon but can include sensorineural hearing loss, vertigo, gait disturbance and disequilibrium from neurosarcoidosis affecting the vestibulocochlear nerves 17 . Middle ear sarcoidosis has also been reported as a sentinel manifestation of the disease, 23 presenting with tinnitus, hearing loss, purulent otorrhoea and otalgia. In this scenario, audiometric findings are mixed or conductive in nature, with CT demonstrating soft tissue masses in the tympanic cavity extending into the mastoid antrum and air cells.…”

Section: Results—ent Manifestations Of Diseasementioning

confidence: 99%

“…Infliximab, a TNF‐α blocking agent, has also been reported as successful in treating ear lobe sarcoidosis refractory to non‐biologic immunosuppressants and intralesional injected corticosteroids 24 . Case reports have suggested that surgical excision of granulation tissue alongside systemic steroid therapy can result in improvement of symptoms 23 …”

Section: Results—ent Manifestations Of Diseasementioning

confidence: 99%

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Sarcoidosis of the ear, nose and throat: A review of the literature

Cereceda-Monteoliva

Rouhani

Rotman

et al. 2021

Clinical Otolaryngology

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Objectives Sarcoidosis is a multisystemic inflammatory disease with extrathoracic manifestations, most commonly affecting the young and middle‐aged, female and Black populations. Diagnosis usually requires evidence of non‐caseating granulomata and, when treated, prognosis is usually favourable. We aim to establish the incidence, clinical features and optimal treatment of ENT manifestations of this disease. Design We performed a PubMed literature review to determine the evidence base supporting this. Results ENT manifestations are present in 5%‐15% of patients with sarcoidosis, often as a presenting feature, and require vigilance for swift recognition and coordinated additional treatment specific to the organ. Laryngeal sarcoidosis presents with difficulty in breathing, dysphonia and cough, and may be treated by speech and language therapy (SLT) or intralesional injection, dilatation or tissue reduction. Nasal disease presents with crusting, rhinitis, nasal obstruction and anosmia, usually without sinus involvement. It is treated by topical nasal or intralesional treatments but may also require endoscopic sinus surgery, laser treatment or even nasal reconstruction. Otological disease is uncommon but includes audiovestibular symptoms, both sensorineural and conductive hearing loss, and skin lesions. Conclusions The consequences of ENT manifestations of sarcoidosis can be uncomfortable, disabling and even life‐threatening. Effective management strategies require good diagnostic skills and use of specific therapies combined with established treatments such as corticosteroids. Comparisons of treatment outcomes are needed to establish best practice in this area.

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Section: Results—ent Manifestations Of Diseasementioning

confidence: 99%

Section: Results—ent Manifestations Of Diseasementioning

confidence: 99%

Sarcoidosis of the ear, nose and throat: A review of the literature

Cereceda-Monteoliva

Rouhani

Rotman

et al. 2021

Clinical Otolaryngology

View full text Add to dashboard Cite

show abstract

“…Infliximab, a TNF-α blocking agent, has also been reported as successful in treating ear lobe sarcoidosis refractory to nonbiologic immunosuppressants and intralesional injected corticosteroids (24). Case reports have suggested that surgical excision of granulation tissue alongside systemic steroid therapy can result in improvement of symptoms (23).…”

Section: Otologic Sarcoidosismentioning

confidence: 99%

Sarcoidosis of the Ear, Nose and Throat: a review of the literature

Cereceda-Monteoliva

Rouhani

Rotman

et al. 2021

Preprint

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Objectives. Sarcoidosis is a multisystemic inflammatory disease with extrathoracic manifestations, most commonly affecting the young and middle-aged, female and black populations. Diagnosis usually requires evidence of non-caseating granulomata and, when treated, prognosis is usually favourable. We aim to establish the incidence, clinical features and optimal treatment of ENT manifestations of this disease. Design. We performed a review of the literature to determine the evidence-base supporting this. Results. ENT manifestations are present in 10-15% of patients with sarcoidosis, often as a presenting feature, and require vigilance for swift recognition and coordinated additional treatment specific to the organ. Laryngeal sarcoidosis presents with difficulty in breathing, dysphonia and cough, and may be treated by Speech and Language Therapy (SLT) or intralesional injection, dilatation or tissue reduction. Nasal disease presents with crusting, rhinitis, nasal obstruction and anosmia, usually without sinus involvement. It is treated by topical nasal or intralesional treatments but may also require endoscopic sinus surgery, laser treatment or even nasal reconstruction. Otological disease is uncommon but includes audiovestibular symptoms, both sensorineural and conductive hearing loss, and skin lesions. Conclusions. The consequences of ENT manifestations of sarcoidosis can be uncomfortable, disabling and even life threatening. Effective management strategies require good diagnostic skills and use of specific therapies combined with established treatments such as corticosteroids. Comparisons of treatment outcomes are needed to establish best practice in this area.

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Otitis Media and Facial Paralysis as Presenting Symptoms of a Primary Middle Ear Sarcoidosis

Cited by 2 publications

References 2 publications

Sarcoidosis of the ear, nose and throat: A review of the literature

Sarcoidosis of the ear, nose and throat: A review of the literature

Sarcoidosis of the Ear, Nose and Throat: a review of the literature

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