Otitis eksternalı köpeklerden izole edilen Pseudomonas aeruginosa suşlarının antibiyotik direnç profilleri

Abstract

Pseudomonas aeruginosa is an important pathogen that is frequently isolated from otitis cases in dogs, known to have high intrinsic and acquired resistance mechanisms to resist most antibiotics, and the ability to develop multiple antibiotic resistance. The aim of this study was to determine the antibiotic resistance profile of P. aeruginosa strains isolated from dogs with otitis externa symptoms. Totally 43 (26.70%) P. aeruginosa strains were isolated from 170 ear swab samples and all these strains were subjected to disk diffusion susceptibility testing and the resistance profiles of the strains were found to be as follows; 100% to trimethoprim sulfamethoxazole, 93.02% to doxycycline, 79.06% to neomycin, 58.13% to oxytetracycline, 34.88% to enrofloxacin, 25.58% to tobramycin, 20.93% to gentamicin, 13.95% to ciprofloxacin, 9.30% to amikacin, 4.65% to polymyxin B. Furthermore, multiple antibiotic resistance was detected in a total of 17 (39.53%) P. aeruginosa strains. As a result, it was understood that the most common Gram-negative bacteria isolated from otitis externa cases of dogs was P. aeruginosa and these isolates have shown high resistance to antibiotics from many antibiotic groups.