Othr-14. Treatment Monitoring of Immunotherapy and Targeted Therapy Using Fet Pet in Patients With Melanoma and Lung Cancer Brain Metastases: Initial Experiences
Abstract:BACKGROUND: Due to the lack of specificity of contrast-enhanced (CE) MRI, both the response assessment and differentiation of progression from pseudoprogression (PsP) following immunotherapy using checkpoint inhibitors (ICI) or targeted therapy (TT) may be challenging, especially when ICI or TT is applied in combination with radiotherapy (RT). Here, we evaluated the value of amino acid PET using O-(2-[18F]fluoroethyl)-L-tyrosine (FET) as a problem-solving tool in comparison to CE-MRI in patients with brain met… Show more
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