Other agents

Abstract

Suggestions based on level III and IV sources)• There is limited evidence to suggest that the progression of certain forms of renal disease is retarded by nonsteroidal anti-inflammatory drugs (NSAIDs), (Level III evidence; several retrospective and prospective cohort studies; mostly surrogate outcome measures; consistent weak effect) and by combined ketaconazole and prednisone (Level II-III evidence; single small cross-over study; clinically relevant outcome; weak effect). However, these benefits are outweighed by the serious side-effects of these medications and their use cannot be currently recommended. BACKGROUND