Ostium Primum Atrial Septal Defect in the Adult

Ce, Martin; Cs, Thomas; Hw, Bender

doi:10.1097/00007611-197608000-00032

Cited by 5 publications

(2 citation statements)

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“…[2] While ostium secundum atrial septal defect is the most common congenital heart defect in the adults, few cases of ostium primum atrial septal defects have been reported, as patients with such anomaly frequently require medical attention at an earlier age. [1] The estimated mean age at death of the patients with ostium primum septal atrial defect is about 36 years,[3] and long-term survival without surgical therapy is very rare. Since the positive impact of surgery on patient's outcome and prognosis, when suspicion is founded, both clinical cardiologists and echocardiographers should investigate for this uncommon disease in the adult.…”

Section: Discussionmentioning

confidence: 99%

“…A few patients with ostium primum atrial septal defects have been reported in adulthood, as these patients frequently require medical attention at an earlier age. [1] We report the case of an adult patient with a recent onset of dyspnoea and decline of general condition, in whom noninvasive and invasive exams clarified the diagnosis of ostium primum defect; surgical closure of the defect was then performed.…”

Section: Introductionmentioning

confidence: 99%

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Large ostium primum interatrial septum defect in asymptomatic elderly patient

Gioia

Mega

Miglionico

et al. 2016

J Cardiovasc Echography

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Ostium primum defect is a congenital malformation involving atrial septum contiguous with atrioventricular valve annulus; it is accompanied by abnormalities in the development of the endocardial cushions, often resulting in associated atrioventricular valves malformations. Few cases have been reported in adulthood because these patients frequently come to medical attention at an earlier age when symptoms such as dyspnea, fatigue, cyanosis, and tendency to underweight occur. Various factors affect the timing of clinical presentation, but the most important is the degree of mitral/tricuspid insufficiency; when valve regurgitation remains moderate, the appearance of symptoms may be delayed for decades. In adult patients, deterioration of clinical status and death are mainly due to the development of arrhythmias or heart block. We present the case of a 67-year-old patient, without previous cardiovascular events, with a new onset of atrial fibrillation, who developed dyspnea and fatigue; echocardiography showed a large interatrial defect localized in the basal portion of the septum, associated with anterior mitral valve cleft and moderate regurgitation. The patient underwent surgical closure of the defect (intraoperatory measures 1,9 × 3 cm) with autologous pericardium patch; a permanent epicardial pacemaker was implanted for the development of complete atrioventricular block in the early postoperative period.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%