Osteosarcoma of the skull. Report of a post-Paget and post-radiation case in an elderly woman

Salvati, Maurizio; Ciappetta, Pasquale; Capoccia, Giovanna; Capone, Raffaela; Raco, Antonino

doi:10.1007/bf00309991

Cited by 8 publications

(2 citation statements)

References 20 publications

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“…After articles were excluded based on our present inclusion and exclusion criteria, finally 87 articles with a total of 137 (48 neuroepithelial tumors, 37 meningiomas, 52 sarcomas) patients in the 1959–2017 period were included in this review, although data is missing regarding overall survival and type of irradiation in a significant proportion of the reports (Figure 1, Table 1, Supplementary Table S1) [14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,…”

Section: Resultsmentioning

confidence: 99%

Secondary Intracranial Tumors Following Radiotherapy for Pituitary Adenomas: A Systematic Review

Yamanaka

Abe

Toshihiko³

et al. 2017

Cancers

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Pituitary adenomas are often treated with radiotherapy for the management of tumor progression or recurrence. Despite the improvement in cure rates, patients treated by radiotherapy are at risk of development of secondary malignancies. We conducted a comprehensive literature review of the secondary intracranial tumors that occurred following radiotherapy to pituitary adenomas to obtain clinicopathological characteristics. The analysis included 48 neuroepithelial tumors, 37 meningiomas, and 52 sarcomas which were published between 1959–2017, although data is missing regarding overall survival and type of irradiation in a significant proportion of the reports. The average onset age for the pituitary adenoma was 37.2 ± 14.4 years and the average latency period before the diagnosis of the secondary tumor was 15.2 ± 8.7 years. Radiotherapy was administered in pituitary adenomas at an average dose of 52.0 ± 19.5 Gy. The distribution of pituitary adenomas according to their function was prolactinoma in 10 (7.2%) cases, acromegaly in 37 (27.0%) cases, Cushing disease in 4 (2.9%) cases, PRL+GH in 1 (0.7%) case, non-functioning adenoma in 57 (41.6%) cases. Irradiation technique delivered was lateral opposing field in 23 (16.7%) cases, 3 or 4 field technique in 27 (19.6%) cases, rotation technique in 10 (7.2%) cases, radio surgery in 6 (4.3%) cases. Most of the glioma or sarcoma had been generated after lateral opposing field or 3/4 field technique. Fibrosarcomas were predominant before 1979 (p < 0.0001). The median overall survival time for all neuroepithelial tumors was 11 months (95% confidence intervals (CI), 3–14). Patients with gliomas treated with radiotherapy exhibited a non-significant positive trend with longer overall survival. The median overall survival time for sarcoma cases was 6 months (95% CI, 1.5–9). The median survival time in patients with radiation and/or chemotherapy for sarcomas exhibited a non-significant positive trend with longer overall survival. In patients treated with radiotherapy for pituitary adenomas, the risk of secondary tumor incidence warrants a longer follow up period. Moreover, radiation and/or chemotherapy should be considered in cases of secondary glioma or sarcoma following radiotherapy to the pituitary adenomas.

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Section: Resultsmentioning

confidence: 99%

Secondary Intracranial Tumors Following Radiotherapy for Pituitary Adenomas: A Systematic Review

Yamanaka

Abe

Toshihiko³

et al. 2017

Cancers

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“…Since then, including our 2 cases, 59 patients in 24 families have been reported (Barry 1961;Bech-Hansen et al 1981;Bottomley et al 1971;Brenton et al 1980;Colyer 1979;Epstein et al 1970;Gilman et al 1985;Harmon and Morton 1966;Lee and Mackenzie 1964;Matejovsky 1977;McIntyre et al 1994;Miller and McLaughlin 1977;Miller 1968;Mulvihill et al 1977;Nassar and Gravanis 1981;Nishida et al 1994;Pohle et al 1936;Robbins 1967;Roberts and Roberts 1935;Salvati et al 1994;Schimke et al 1974;Smith et al 1980;Swaney 1973;Werner 1930). The authors collected data from 59 cases, including the age and sex of the patient, the anatomical site, and previous disorders, treatment, and prognosis.…”

Section: Discussionmentioning

confidence: 99%