Osteosarcoma of the maxilla presenting as a chronic pyogenic abscess: A case report

Sain, Baijaeek; Gupta, Akash; Ghosh, Supriti; Mondal, Radha Raman; Bhattacharya, Samir; Ghose, Aruni

doi:10.1016/j.ijscr.2021.106425

Cited by 3 publications

(4 citation statements)

References 21 publications

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“…10 Craniofacial OS accounts for only 1% of all head and neck malignancies. 11 Jaws are the fourth most commonly afflicted site but constitute only approximately 6 to 7% of all skeletal cases of OS. 12,13 OS of jaw bones have some distinct features from those of long bones such as older age at presentation with local recurrences being difficult to control, which leads to death of the patients.…”

Section: Discussionmentioning

confidence: 99%

Osteosarcoma of Maxilla - An Unusual Entity: Case Report and Review of Literature

HAMEED,

ANTO,

VENGAL

et al. 2023

Cumhuriyet Dental Journal

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Malignant bone tumors are rare malignancies of which osteosarcomas are the most common considering bone marrow tumors are excluded. They account for approximately 6-10% of jaw lesions and affect the mandible more often than the maxilla. A review of literature shows there are rare cases of osteosarcomas reported in the maxilla; however, given the lack of specific signs and a diverse range of radiographic features, the diagnosis is often difficult and requires a multidisciplinary discussion. This is the case report of a 56-year-old female presenting a well-defined, dome-shaped firm swelling with radiographic features of extensive destruction of the buccal cortical bone in the maxillary right posterior region. Early diagnosis helped in the better prognosis of the patient. She is undergoing regular follow-ups to ensure no recurrences of this aggressive lesion. Osteosarcoma of the jaw is difficult to diagnose and manage due to the high frequency of errors in biopsy results, the few specific radiological characteristics, and difficulties in appropriate resections because of the proximity to vital structures. Through the years, the survival of patients has greatly improved, due to an aggressive systemic approach and refined surgical and reconstructive techniques. However, for purposes of management, emphasis should be laid on the aggressiveness of this lesion which warrants an early identification and diagnosis of the lesion followed by prompt treatment.

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Section: Discussionmentioning

confidence: 99%

Osteosarcoma of Maxilla - An Unusual Entity: Case Report and Review of Literature

HAMEED,

ANTO,

VENGAL

et al. 2023

Cumhuriyet Dental Journal

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“…Surgical excision with negative margins when possible combined with adjuvant radiation and/or chemotherapy appears to offer the best survival outcomes [6,17,24,25].…”

Section: Discussionmentioning

confidence: 99%

“…Diagnosing osteosarcoma is very challenging and osteosarcoma is often misdiagnosed as osteomyelitis due to the nonspecificity of its symptoms upon initial presentation [6,23,24].…”

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confidence: 99%

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Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man

et al. 2022

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Sarcomas in the head and neck area are rare diseases with an incidence of under 1% of all head and neck malignant tumours. Osteosarcomas or osteogenic sarcomas consist of neoplastic cells that produce osteoid bone or immature bone. Sarcomas develop more in the mandible than the maxilla. The exact diagnosis of different types of sarcomas is based on the immunohistochemical investigation. These rare tumours are of mesenchymal origin; osteosarcomas and chondrosarcomas are the most common types—Ewing’s sarcomas. The use of proton beam radiotherapy in the treatment of osteosarcoma of the maxilla is rarely reported in the literature. We present a case of successfully treated (surgery and proton beam radiotherapy) poorly differentiated highly aggressive osteosarcoma in the ethmoids and maxillary sinus and morbidity after the treatment. We were presented with a case of a 65-year-old man with anaesthesia and palsy of the right face. The stomatology department performed the extraction of a tooth. One month later, the wound was still open. The histology showed an osteogenic sarcoma in the area of the wound. The oncologist and maxillofacial surgeons in a catchment hospital recommended a nonsurgical approach. Hence, we performed a radical maxillectomy and ethmoidectomy, after which we continued with proton bean radiotherapy. The patient is now five years after therapy without signs of sarcoma; however, he has blindness in the right eye and reduced vision in the left eye, as well as gliosis of the brain, vertigo, tinnitus, trismus, and ancylostomiases. Head and neck osteosarcomas treatment is considered a complex multidisciplinary task. It is currently argued that there is no clear therapeutic protocol for successful treatment. Innovations in treatment modalities such as proton beam radiotherapy appear to have potential, although their effects on long-term morbidity and survival outcomes are still undetermined. We present a rare case report of an osteosarcoma of the maxilla involving an innovative, successful treatment procedure combining surgical excision followed by proton beam radiotherapy. This treatment approach may enable maximum tumour control. This protocol has not been adequately described in the world literature for this diagnosis.

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A rare case of osteosarcoma of the nasal cavity with extension to the base of the skull and orbit

Shelesko,

Nikonova,

Chernikova

et al. 2023

Endosk. khir.

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Osteosarcoma of the maxilla presenting as a chronic pyogenic abscess: A case report

Cited by 3 publications

References 21 publications

Osteosarcoma of Maxilla - An Unusual Entity: Case Report and Review of Literature

Osteosarcoma of Maxilla - An Unusual Entity: Case Report and Review of Literature

Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man

A rare case of osteosarcoma of the nasal cavity with extension to the base of the skull and orbit

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