1963
DOI: 10.1016/0002-9610(63)90407-0
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Osteoradionecrosis of the mandible and its treatment

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1971
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Cited by 27 publications
(4 citation statements)
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“…Since higher radiation dosage is associated with was associated with significantly higher incidence of osteoradionecrosis, [26][27][28] we examined the dosage used in the patients, and we found that the radiation dosage did not differ between groups in our study (muscle vs. nonmuscle ¼ 61.6 AE 6.7 vs. 60.7 AE 7.0, p ¼ 0.661, Independent t-test), which was the definitive dosage for oropharyngeal cancer. Trauma or mandibulectomy is a risk for ORN, 10,29 but the defect size was even larger and bone length was even longer in muscle group. Treatment of ORN or osteomyelitis needs multiple treatment modalities, including the combination of administration of antibiotics, surgical debridement of infected bone, and a perforator flap coverage for a better outcome.…”
Section: Discussionmentioning
confidence: 93%
“…Since higher radiation dosage is associated with was associated with significantly higher incidence of osteoradionecrosis, [26][27][28] we examined the dosage used in the patients, and we found that the radiation dosage did not differ between groups in our study (muscle vs. nonmuscle ¼ 61.6 AE 6.7 vs. 60.7 AE 7.0, p ¼ 0.661, Independent t-test), which was the definitive dosage for oropharyngeal cancer. Trauma or mandibulectomy is a risk for ORN, 10,29 but the defect size was even larger and bone length was even longer in muscle group. Treatment of ORN or osteomyelitis needs multiple treatment modalities, including the combination of administration of antibiotics, surgical debridement of infected bone, and a perforator flap coverage for a better outcome.…”
Section: Discussionmentioning
confidence: 93%
“…These imaging features were not associated with the severity of ORN [ 40 , 41 ]. However, in the present study, multivariate analysis indicated that non-sequestration was a risk factor for a poor prognosis.…”
Section: Discussionmentioning
confidence: 99%
“…Mandibular osteoradionecrosis (ORN) is a serious complication of radiation therapy for neoplasms of the oral cavity, oropharynx, nasopharynx, and parotid gland, with a varying reported incidence of 5% to 22% [9, 11, 18, 19]. The higher incidence of mandibular involvement has been attributed to its lower blood supply compared with the maxilla and the compact bone structure [11, 20].…”
Section: Osteoradionecrosismentioning
confidence: 99%