Osteoporotic osseointegration: therapeutic hallmarks and engineering strategies
Jiayao Chen,
Zhuowen Hao,
Hanke Li
et al.
Abstract:Osteoporosis is a systemic skeletal disease caused by an imbalance between bone resorption and formation. Current treatments primarily involve systemic medication and hormone therapy. However, these systemic treatments lack directionality and are often ineffective for locally severe osteoporosis, with the potential for complex adverse reactions. Consequently, treatment strategies using bioactive materials or external interventions have emerged as the most promising approaches. This review proposes twelve micro… Show more
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