Osteoporosis prediction from the mandible using cone-beam computed tomography

Abstract

PurposeThis study aimed to evaluate the use of dental cone-beam computed tomography (CBCT) in the diagnosis of osteoporosis among menopausal and postmenopausal women by using only a CBCT viewer program.Materials and MethodsThirty-eight menopausal and postmenopausal women who underwent dual-energy X-ray absorptiometry (DXA) examination for hip and lumbar vertebrae were scanned using CBCT (field of view: 13 cm×15 cm; voxel size: 0.25 mm). Slices from the body of the mandible as well as the ramus were selected and some CBCT-derived variables, such as radiographic density (RD) as gray values, were calculated as gray values. Pearson's correlation, one-way analysis of variance (ANOVA), and accuracy (sensitivity and specificity) evaluation based on linear and logistic regression were performed to choose the variable that best correlated with the lumbar and femoral neck T-scores.ResultsRD of the whole bone area of the mandible was the variable that best correlated with and predicted both the femoral neck and the lumbar vertebrae T-scores; further, Pearson's correlation coefficients were 0.5/0.6 (p value=0.037/0.009). The sensitivity, specificity, and accuracy based on the logistic regression were 50%, 88.9%, and 78.4%, respectively, for the femoral neck, and 46.2%, 91.3%, and 75%, respectively, for the lumbar vertebrae.ConclusionLumbar vertebrae and femoral neck osteoporosis can be predicted with high accuracy from the RD value of the body of the mandible by using a CBCT viewer program.

Detecting the effect of bisphosphonates during osteoporosis treatment on jawbones using multidetector computed tomography: The OSTEOSYR project

“…Indices developed by Barngkgei et al. and Koh and Kim were used . Briefly, on the axial image at the mental foramen area, the anteroposterior cursor was made tangent to the bone (Figure A).…”

“…The use of dental radiographs for osteoporosis screening has been extensively evaluated; however, using computed tomography techniques (multidetector computed tomography [MDCT] or cone‐beam computed tomography [CBCT]) for such a purpose has been infrequently investigated due to radiation dose concerns . In addition, these techniques are not the usual prescribed imaging techniques for dental patients, which means they would be of low value for opportunistic screening.…”

A Novel Method for Estimation of Femoral Neck Bone Mineral Density Using Forearm Images from Peripheral Cone Beam Computed Tomography

“…Even though the femoral neck and the forearm bones are not directly associated with each other, similar research effort has been conducted on the relationship between BMDs from different sites. In [25][26][27], the results showed that that some parameters from the cortical bone in distal radius and ulnar on anteroposterior radiograph could reflect the femoral neck BMD. In [25], the distal radius BMD was correlated with the ratio of the outside cortical shell diameter to the inside cortical shell diameter at the metaphyseal/diaphyseal junction.…”

“…In [25], the distal radius BMD was correlated with the ratio of the outside cortical shell diameter to the inside cortical shell diameter at the metaphyseal/diaphyseal junction. In [26], radiologic density of dental structure from CBCT imaging could provide information of lumbar vertebra and femoral neck. In [27], the radial bicortical widths were measured at 50 and 70 mm proximal to the distal ulnar articular surface, and the mean bicortical width was compared with each patient's femoral BMD.…”

“…In [26], radiologic density of dental structure from CBCT imaging could provide information of lumbar vertebra and femoral neck. In [27], the radial bicortical widths were measured at 50 and 70 mm proximal to the distal ulnar articular surface, and the mean bicortical width was compared with each patient's femoral BMD.…”