Osteoporosis in Indian Patients Undergoing Elective Arthroplasty and Spinal Procedures: An Observational Study

Dave, D. J.; Bhattacharjee, Sujoy K; Shah, Dilip D.; Mascerhans, Amrithlal; Dey, Paresh C; Arumugan, Subramanian; Mehra, Vikas; Agarwal, V.K.; Garg, Sandeep; Gore, Satish Chandra; Choudhry, Rajiv Raj; Mahajan, Manish; Bharat, Suyash

doi:10.7759/cureus.27275

Cited by 2 publications

(2 citation statements)

References 53 publications

(89 reference statements)

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“…The osteoporosis prevalence varied from 9.6% to 50.8% in included studies. Studies were carried out in eight countries including Spin [ 21 ], Germany [ 22 ], Sweden [ 17 ], France [ 23 ], China [ 18 , 24 ], Korea [ 9 ], India [ 25 ], America [ 8 , 26 ]. The mean age of participants in individual studies varied from 60.9 to 71.2.…”

Section: Resultsmentioning

confidence: 99%

Prevalence of osteoporosis in spinal surgery patients older than 50 years: A systematic review and meta-analysis

Fan

Yan

et al. 2023

PLoS ONE

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Introduction In spine surgery, poor bone condition is associated with several complications like adjacent segment fractures, proximal junctional kyphosis, and screw loosening. Our study explored the prevalence of osteoporosis in spinal surgery patients older than 50 years through a systematic review and meta-analysis. Methods This systematic review and meta-analysis were conducted according to the PRISMA criteria. Three electronic databases, including PubMed, EMBASE, and Web of Science, were searched from inception to August 2022. We used the random-effects model to calculate the overall estimates, and the heterogeneity was measured using Cochran’s Q and I2 tests. Meta-regression and subgroup analyses were used to determine the source of the heterogeneity. Results Based on the inclusion and criteria, we chose ten studies with 2958 individuals for our analysis. The prevalence of osteoporosis, osteopenia, and osteoporosis/osteopenia in the spinal surgery patients was 34.2% (95%CI: 24.5%–44.6%), 43.5% (95%CI: 39.8%–47.2%), and 78.7% (95%CI: 69.0%–87.0%), respectively. Regarding different diagnoses, the prevalence was highest in patients with lumbar scoliosis (55.8%; 95%CI: 46.8%-64.7%) and the lowest in patients with cervical disc herniation (12.9%; 95%CI: 8.1%-18.7%). In age groups 50–59, 50–69,70–79, the prevalence was 27.8%, 60.4%, 75.4% in females, and 18.9%, 17.4%, 26.1% in males. Conclusions This study showed a high prevalence of osteoporosis in patients undergoing spine surgery, especially in females, people of older age, and patients who received degenerative scoliosis and compression fractures. Current osteoporosis screening standards for patients undergoing spine surgery may not be adequate. Orthopedic specialists should make more efforts regarding preoperative osteoporosis screening and treatment.

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Section: Resultsmentioning

confidence: 99%

Prevalence of osteoporosis in spinal surgery patients older than 50 years: A systematic review and meta-analysis

Fan

Yan

et al. 2023

PLoS ONE

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“…12 Osteoporosis can be preexisting in the patient or occur as a result of arthroplasty affecting more than 200 million people worldwide. 13 One in three women and one in five men over 50 will have an osteoporotic fracture in their lifetime. 14 This condition can impair the quality of life and health of the people with it and impose a high economic burden on the healthcare system.…”

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confidence: 99%

Teriparatide therapy in joint replacement surgery: mitigating complications and improving patient outcomes in osteoarthritis

Chaudhari

2023

Int J Res Orthop

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Background: Teriparatide, a synthetic form of parathyroid hormone, has gained significant recognition as an effective treatment for osteoporosis. Its ability to stimulate bone formation and improve bone mineral density has made it a valuable therapeutic option in managing this prevalent skeletal disorder. However, its safety and potential benefits in preventing bone mineral density (BMD) loss after joint replacement surgery and post-surgical complications have yet to be extensively investigated. Methods: This retrospective study included 32 patients who received teriparatide following joint replacement surgery for osteoarthritis. The analysis focused on assessing teriparatide’s effectiveness in any reductions in post-surgical complications and adverse events, if any. Results: No teriparatide-related adverse events and post-surgical complications were reported during the follow-ups and the entire study duration. Conclusions: Teriparatide demonstrated effectiveness in joint replacement patients. Further research is needed to explore long-term benefits and effects on implant longevity.

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Osteoporosis in Indian Patients Undergoing Elective Arthroplasty and Spinal Procedures: An Observational Study

Cited by 2 publications

References 53 publications

Prevalence of osteoporosis in spinal surgery patients older than 50 years: A systematic review and meta-analysis

Prevalence of osteoporosis in spinal surgery patients older than 50 years: A systematic review and meta-analysis

Teriparatide therapy in joint replacement surgery: mitigating complications and improving patient outcomes in osteoarthritis

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