Abstract:Background: Osteoporosis is a global age-related health problem in both male and female elderly, affecting the microstructure of bone. Although osteoporosis is normally associated with old age and estrogen deficiency, diabetes mellitus (DM), also contributes to and/or aggravates bone loss in osteoporotic patients Diabetes can affect bone through multiple pathways including obesity, changes in insulin levels, higher concentrations of advanced glycation end products in collagen, microangiopathy, inflammation and… Show more
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