2019
DOI: 10.1002/jbm4.10231
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Osteoporosis Epidemiology Among Adults With Cerebral Palsy: Findings From Private and Public Administrative Claims Data

Abstract: Individuals with cerebral palsy (CP) have an increased risk for the early development of osteoporosis; however, little is known about the epidemiology of osteoporosis for adults with CP, which is vital to inform clinical practice for osteoporosis prevention, treatment, and management. The purpose of this cross‐sectional study was to determine sex‐stratified prevalence of osteoporosis among adults with CP, as compared with adults without CP. Data from 2016 were extracted from Optum Clinformatics Data Mart (priv… Show more

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Cited by 26 publications
(35 citation statements)
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(82 reference statements)
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“…However, findings were derived from privately insured adults with cerebral palsy, which reflects a healthier segment of the cerebral palsy population. 38 , 39 This is evidenced by the lower than expected prevalence of intellectual disabilities found in this study (20.3%) compared with a population-based study of cerebral palsy (45%). 24 Therefore, generalizability may be limited to the healthier segment of the cerebral palsy population.…”
Section: Discussioncontrasting
confidence: 60%
“…However, findings were derived from privately insured adults with cerebral palsy, which reflects a healthier segment of the cerebral palsy population. 38 , 39 This is evidenced by the lower than expected prevalence of intellectual disabilities found in this study (20.3%) compared with a population-based study of cerebral palsy (45%). 24 Therefore, generalizability may be limited to the healthier segment of the cerebral palsy population.…”
Section: Discussioncontrasting
confidence: 60%
“…First, data were from a private payer claims database, which likely reflects the higher‐functioning segment of the CP population. This speculation is based on differences in enrolment criteria between private and public insurance types, medical needs of individuals with CP based on insurance coverage, and prevalent chronic diseases for adults with pediatric‐onset disabilities (higher among publicly vs privately insured), including CP 25,29 . It is important to note that while the prevalence estimates of the exposure and outcome may reflect the higher‐functioning segment of the CP population, it is plausible that the direction, and even the strength, of the exposure‐outcome association observed in this study is representative of what occurs in the general CP population.…”
Section: Discussionmentioning
confidence: 85%
“…Second, adults with vs without CP may be more likely to be taking several medications (eg, polypharmacy) to manage their greater disease profiles, 29 which may lead to drug–drug interactions and reduce the long-term efficacy of osteoporosis medication. Third, given the poorly developed 7 , 8 , 46 and preserved 13–15 , 47 musculoskeletal tissue throughout the lifespan, it is possible that the needs of the musculoskeletal system from adults with CP over time exceed the skeletal benefit of osteoporosis medication alone in the long term.…”
Section: Discussionmentioning
confidence: 99%