Osteoporosis and Fracture Risk among Older US Asian Adults

Lo, Joan C.; Yang, Wei; Park-Sigal, Jennifer J.; Ott, Susan M.

doi:10.1007/s11914-023-00805-7

Cited by 5 publications

(2 citation statements)

References 143 publications

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“…The development of osteoporosis can be attributed to two factors. The first aspect is the peak bone mass (PBM) accumulation during puberty, and the second is the bone mass loss in old age [ 4 , 5 ]. Bone mass loss can be determined by various factors, including genetics, environment, diet, and others [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…The first aspect is the peak bone mass (PBM) accumulation during puberty, and the second is the bone mass loss in old age [ 4 , 5 ]. Bone mass loss can be determined by various factors, including genetics, environment, diet, and others [ 5 , 6 ]. Therefore, to reduce the high morbidity and mortality caused by osteoporosis in elderly individuals, it is essential to recognize and manage modifiable factors that contribute to osteoporosis.…”

Section: Introductionmentioning

confidence: 99%

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The association between remnant cholesterol and bone mineral density in US adults: the National Health and Nutrition Examination Survey (NHANES) 2013–2018

Xiao,

Wang,

et al. 2024

Lipids Health Dis

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Background Previous evidence showed a possible link of dyslipidemia with bone health. Nevertheless, the correlation of remnant cholesterol (RC) with bone mineral density (BMD) has yet to be well investigated. This study investigated the association of RC with total spine BMD in general Americans. Methods This study explored the relationship of RC with total spine BMD in subjects aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) 2013–2018. After adjusting for covariates, multivariate linear regression and stratified analyses were conducted to determine the correlation of serum RC with total spine BMD in adult Americans. Restricted cubic spline (RCS) was applied to examine the nonlinear association of serum RC with total spine BMD. Results This study included 3815 individuals ≥ 20 years old, 1905 (49.93%) of whom were men and 1910 (50.07%) of whom were women. After adjusting for all covariates, the results showed a negative relationship of serum RC with total spine BMD (β= -0.024, 95% CI: -0.039, -0.010). The interaction tests of age, sex, race, and BMI showed no statistically significant effects on the association. The RCS also indicated a negative linear correlation of serum RC with total spine BMD (nonlinear P = 0.068, overall P < 0.001). Moreover, RC had a stronger effect on total spine BMD than total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). Conclusions This study found that serum RC was negatively related to total spine BMD in U.S. adults. These findings emphasized the important role of RC in bone health in American adults.

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Section: Introductionmentioning

confidence: 99%