Osteoporosis: A Possible Modifying Factor in Oral Bone Loss

Jeffcoat, M. K.

doi:10.1902/annals.1998.3.1.312

Cited by 108 publications

(69 citation statements)

References 37 publications

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“…These data agree with the literature showing a positive association between osteoporosis, tooth loss and edentulism [31]. In this respect, evidence indicates that treatments designed to increase BMD such as hormone replacement and bisphosphonate therapy may be associated with less tooth loss [32].…”

Section: Discussionsupporting

confidence: 92%

Comparative study of axial and femoral bone mineral density and parameters of mandibular bone quality in patients receiving dental implants

et al. 2007

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Introduction: In view of the increase in the life expectancy of humans and in edentulism of the population above 50 years of age, in which the prevalence of osteoporosis is also higher, it is fundamental to better understand the effects of systemic bone mass loss on the healing process of dental implants and to determine the quality of the bone that surrounds them. The objective of the present study was to compare systemic osteoporosis (axial and femoral) and parameters of mandibular bone quality, and to evaluate osseointegration in postmenopausal women receiving dental implants. Methods: The sample consisted of 39 women aged 48-70 years, 19 with a densitometric diagnosis of osteoporosis in the lumbar spine and femoral neck and 20 controls with a normal densitometric diagnosis. Bone mineral density was measured in the patients and controls by dual-energy X-ray absorptiometry. Eighty-two osseointegrated dental implants were placed in the mandible, 39 of them in the osteoporosis group and 43 in the control group. Mandibular bone quality was evaluated by classifying mandibular inferior cortical and trabecular bone on panoramic radiographs and by histomorphometric analysis of a mandibular bone biopsy. Osseointegration was analyzed after 9 months. Results: No significant difference was observed between patients with osteoporosis and controls when comparing individuals with a normal cortex and those with a severely or moderately eroded cortex determined on panoramic radiographs, although patients with MEC/SEC had lower femoral neck BMD than those with NC (0.688 ± 0.17 vs. 0.814 ± 0.144 g/cm 2 , P<0.012). Histomorphometric analysis also revealed no difference in the parameters of bone formation or resorption between the two groups. Implant failure was observed in only one case. Conclusion: We conclude that there is an association between low femoral neck BMD and poor mandibular bone quality as assessed by panoramic radiography. The loss of one implant (1.2%) is compatible with the literature and cannot be attributed to systemic osteoporosis.

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Section: Discussionsupporting

confidence: 92%

Comparative study of axial and femoral bone mineral density and parameters of mandibular bone quality in patients receiving dental implants

et al. 2007

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“…4 Residual ridge and alveolar bone density showed a significant relationship to total body calcium and regional bone loss in a study conducted by Kribbs et al 13 …”

Section: Relationship Between Systemic and Mandibular Bone Mineral Dementioning

confidence: 94%

“…steroids). 4 National Osteoporosis Foundation recommend bone mass measurements in postmenopausal women assuming they have risk factors for osteoporosis in addition to age, gender and estrogen deficiency.…”

Section: Clinical Featuresmentioning

confidence: 99%

“…In clinical trials, bisphosphonate Aldendronate has been found to reduce the risk of progressive loss of alveolar bone. 4 These management strategies require further validation. Reports of bisphosphonate associated osteonecrosis (BON) of jaw associated with the use of IV bisphosphonates were first published in 2003.…”

Section: Common Strategies For Treatment Of Osteoporosis and Periodonmentioning

confidence: 99%

“…3 Osteoporosis before fracture is termed a 'silent disease'. 4 Hence, the stress is on early identification of the disease and its prevention. Unfortunately, the techniques available involve special radiographic procedures and are relatively expensive.…”

Section: Introductionmentioning

confidence: 99%

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