Osteonecrosis of the Femoral Head with Collapsed Medial Lesion

Abstract

A 60-year-old female experienced the gradual onset of left hip pain without any triggering event. Radiographs showed vertical sclerosis in the center of the femoral head and the lesion inside the boundary demonstrated diffuse bony sclerosis. No collapse was observed at the weight-bearing portion on radiograph. However, computed tomography showed a subchondral collapse at the medial lesion. On T2-weighted magnetic resonance imaging, the necrotic lesion showed diffuse high-intensity signals that indicated a prominent repair process. Bone biopsy diagnosed osteonecrosis with associated prominent appositional bone and vascular granulation tissue.

Clinical effect of hyperbaric oxygen therapy in the treatment of femoral head necrosis

“…After taking the drug, the action is quick and pain relief is remarkable; however, the maintenance time is short and the biggest problem is the adverse drug reaction [41][42][43][44]. Although celecoxib is the nonsteroidal antiinflammatory analgesic drug eliciting the smallest gastrointestinal tract reaction, clinical use still results in gastrointestinal discomfort in numerous patients.…”