Osteonecrosis: Historical Perspective

Steinberg, Marvin E.; Steinberg, David R.

doi:10.1007/978-3-642-35767-1_1

Cited by 11 publications

(11 citation statements)

References 74 publications

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“…These involve three-axis directions, varus-valgus, flexion-extension, and anterior-posterior rotation. These procedures are technically demanding and are popular in Asia, though less in other regions [ 3 , 28 ].…”

Section: Osteotomymentioning

confidence: 99%

“…Various surgical techniques have been reported for the use of bone grafts for the treatment of ONFH. In the 1930s, Phemister first reported a surgical procedure of a non-vascularized bone graft from the tibia for the treatment of ONFH [ 28 ]. Since then, newer techniques such as the lightbulb and trapdoor non-vascularized bone graft have been used with good results [ 29 ].…”

Section: Bone Graftingmentioning

confidence: 99%

“…Another technique for bone grafting is vascularized option. Vascularized fibular graft was introduced in 1979 and consists of a fibular graft together with its vascular supply and harvested directly into the necrotic lesion of the femoral head [ 28 ]. Vascularized fibular graft is one of the technically difficult orthopedic surgeries which require technique of microvascular surgery.…”

Section: Bone Graftingmentioning

confidence: 99%

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Joint-preserving regenerative therapy for patients with early-stage osteonecrosis of the femoral head

2016

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Osteonecrosis of the femoral head is an intractable disease often occurring in patients aged 30–40 years that can cause femoral head collapse, pain, and gait disturbance. Background factors, including corticosteroid use, alcohol intake, and idiopathic causes, have been indicated. It is estimated that 70–80 % of osteonecrosis patients experience femoral head collapse, for which total hip arthroplasty is considered the most effective treatment, even in young patients. Thus, there is a crucial need for developing a minimally invasive regenerative therapy as a preventive surgery for femoral head collapse: this has been an important area of research in the past decades. Core decompression, the most popular minimally invasive surgery for osteonecrosis of the femoral head, has been used for a long time; however, it has been insufficient to prevent femoral head collapse. For further improvement in therapeutic efficacy, cell transplantation and the use of artificial bone and growth factors have been proposed in addition to core decompression. Since 2000, newer therapies such as autologous bone marrow cell transplantation and the embedding of metal implant rods have been developed in Europe and the USA; however, these approaches have yet to become a global standard. This practical review summarizes applied state-of-the-art regenerative therapy-based core decompression. We introduce the clinical application of recombinant human fibroblast growth factor (rhFGF)-2-impregnated gelatin hydrogel for patients with precollapse osteonecrosis of the femoral head. Radiography and computed tomography have confirmed bone regeneration inside the femoral heads around the region of rhFGF-2 gelatin hydrogel administration. With further development, the minimally invasive method, which can be expected to promote bone regeneration in necrotic areas, could become a useful early-stage treatment for osteonecrosis of the femoral head. Patients can resume their daily routine soon after surgery, and the procedure is inexpensive. As such, it is a promising regenerative therapy that can be actively employed in osteonecrosis of the femoral head before femoral head collapse.

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Section: Osteotomymentioning

confidence: 99%

Section: Bone Graftingmentioning

confidence: 99%

Section: Bone Graftingmentioning

confidence: 99%

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Joint-preserving regenerative therapy for patients with early-stage osteonecrosis of the femoral head

2016

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“…Osteonecrosis (ON) was first described in 1738 by Alexander Munro [1]. In 1794, James Russell, professor of clinical Surgery in Edinburgh, published his classic essay on bone necrosis, which was one of the first detailed pathological descriptions of this disease.…”

mentioning

confidence: 99%

Bipolar Hemiarthroplasty vs Total Arthroplasty of the Patients with Aseptic Necrosis of the Femoral Head - 20 year retrospective study

Patrascu¹,

Savin²,

Mihăilescu³

et al. 2018

Rev. Chim.

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We evaluated 1541 patients with aseptic necrosis of the femoral head who underwent prosthetic surgery over a period of 20 years and assessed each implant survival rate depending on the surgucal technique used. The patients were divided into two groups. The first group contained patients with stage II and III of aseptic necrosis, while the second group contained patients with coxarthrosis secondary to the aseptic necrosis of the femoral head. In 20 years, the revision of the bipolar prosthesis in patients with NACF stage III was rated at 1.65%, p=0.0005 and the total prosthesis was rated 7.41%, in patients with secondary NACF coxarthrosis, in spite of 3.98% which was in patients with NACF, p=0.002. The cotyloid was the most frequent cause for the bipolar prosthesis revision and the aseptic loosening of the cup was the most common cause for the total prosthesis revision in patients with secondary NACF coxarthrosis.

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“…A more detailed synopsis of the historical prospective of ARCO can be found in a recently published book entitled Osteonecrosis. 2 Osteonecrosis of the hip can sometimes pose challenges to orthopaedists and other medical professionals involved in the musculoskeletal field. It is not uncommon to encounter a patient who visited multiple physicians and did not receive the correct diagnosis or care.…”

mentioning

confidence: 99%