Osteonecrosis asintomática de la cadera en los pacientes infectados por el virus de inmunodeficiencia humana

Lamas, José Luis; Ocampo, Antonio; Martínez-Vázquez, C.; Miralles, Celia; Longueira, Rebeca; Arias, Mercedes; Sopeña, B.; Rivera, Alberto; Portela, Daniel

doi:10.1016/j.eimc.2009.06.003

Cited by 9 publications

(4 citation statements)

References 27 publications

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“…Although individuals who misuse drugs are thought to be at increased risk of inflammatory arthropathies, the indication for surgery in this population is complicated by a higher risk of infection [7,8]. The results of this study show that patients who misuse drugs face prolonged hospital lengths of stay and higher odds of leaving against medical advice, mortality and complications following primary THA or TKA.…”

Section: Discussionmentioning

confidence: 78%

“…The lifetime prevalence of drug abuse and dependence among U.S. adults is estimated at 7.7% and 2.6%, respectively [6]. The risk of secondary osteoarthritis among drug users is thought to be higher than the general population due to increased rates of osteonecrosis of the femoral head and inflammatory arthropathies due to repetitive bacteremia [7,8]. Additionally, when joint arthroplasty is considered, the risk of a septic complication is of concern as injection or inhalation of drugs is felt to increase the risk of infection [9,10].…”

mentioning

confidence: 99%

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Outcomes Following Primary Total Hip or Knee Arthroplasty in Substance Misusers

Best

Buller

Klika

et al. 2015

The Journal of Arthroplasty

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Section: Discussionmentioning

confidence: 78%

mentioning

confidence: 99%

Outcomes Following Primary Total Hip or Knee Arthroplasty in Substance Misusers

Best

Buller

Klika

et al. 2015

The Journal of Arthroplasty

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“…The association of avascular necrosis and HIV infection was established in Europe and Asia, in adults as well as in children [1,10,[12][13][14][15]. The prevalence of asymptomatic hip necrosis in HIV patients was 41% in a study conducted in Spain [12].…”

Section: Discussionmentioning

confidence: 99%

Epiphyseal Necrosis in Patients with HIV Infection and Free from Sickle Cell Disease

Es¹,

Houzou²,

Kakpovi³

et al. 2018

J Autoimmune Disord

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We report a series of 17 cases of epiphyseal necrosis observed in nine women aged 40 years on average. These nine patients, with HIV1 infection, were free from other risk factors of bone necrosis, especially SS and sickle cell disease. The necrosis affected the two femoral heads in 6 patients, one femoral head in one patient, one humeral head in one patient, and the two femoral heads and one humeral head in the last patient. The necrosis revealed HIV1 infection in 4 patients. It has complicated the course of HIV1 infection in other 5 patients, despite antiretroviral therapy.These observations argue in favor of the etiological role of HIV infection in the occurrence of epiphyseal necrosis. The relatively young age of the patients and the high number of bilateral involvement testify to the severity of the necrosis induced by HIV.

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“…Since 1990 [41] numerous studies have related HIV infections with a greater risk for osteonecrosis. Some of the more recent articles have asserted that HIV patients have a 100 times greater risk of developing osteonecrosis and a 4.1% prevalence of asymptomatic ischemic necrosis of the femoral head (INFH) [42, 43].…”

Section: Hiv Infectionmentioning

confidence: 99%

Special Issues Involving Periprosthetic Infection in Immunodeficiency Patients

Tornero¹,

Riba²,

García-Ramiro³

2013

TOORTHJ

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Chronic systemic illnesses such as diabetes mellitus, chronic kidney disease (CKD), liver cirrhosis, neoplasia, etc. have been clearly associated with high rates of SWI. However, the exact mechanisms underlying these observations are still under investigation.Chronic kidney disease (CKD) is a growing problem in our society. Many of these patients will require an arthroplasty and it appears that the prosthetic infection risk for these types of patients is much higher than in the normal population. The risk of complications due to infection seems to be lower in patients with kidney transplants than in patients undergoing haemodialysis. Both prophylaxis and treatment of infection in patients with CKD should be carried out with a strict monitoring of potentially nephrotoxic antibiotics.The literature on the prognosis and risk of infection in patients with haematopoietic stem cell transplant is scarce and occasionally contradictory. The optimal time for the surgery should be determined by taking into account the immunological state of the patient and should be avoided, as much as possible, during the first year after the HSCT.Child’s classification system is the most widely used method of stratifying the surgical risk for patients with cirrhosis; the infection appeared to be associated in a statistically significant way with advanced age and a Child B pre-operative classification.The prevention of prosthetic joint infections in HIV-infected patients should not be significantly different from the prevention for any other patient. Those patients that receive adequate antiretroviral treatment and periodic laboratory control show infection rates and periprosthetic complications that are similar to those for patients not affected by HIV. Therefore, the patient’s level of immunodeficiency is the most important prognostic factor for prosthetic infection.The particular immunological condition of these patients can lead to infections due to particular microorganisms that immunocompetent patients do not have to deal with. Of all possibilities, because of their frequency and difficulty to treat, infections caused by methicillin-resistant S. aureus and fungus are highlighted.

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Osteonecrosis asintomática de la cadera en los pacientes infectados por el virus de inmunodeficiencia humana

Cited by 9 publications

References 27 publications

Outcomes Following Primary Total Hip or Knee Arthroplasty in Substance Misusers

Outcomes Following Primary Total Hip or Knee Arthroplasty in Substance Misusers

Epiphyseal Necrosis in Patients with HIV Infection and Free from Sickle Cell Disease

Special Issues Involving Periprosthetic Infection in Immunodeficiency Patients

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