Osteomyelitis Therapy – Hyperbaric Oxygen as an Adjunct in Treatment of Osteomyelitis of the Jaws

Schmutz, Jörg

doi:10.1007/978-3-540-28766-7_10

Cited by 4 publications

(3 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This specific model can reach up to 2.4 Atmospheres Absolute (ATA), which can increase the O2 tissue pressure by 1200% [25]. In osteomyelitis, the infected bone is often in a hypoxic state, which can impair the bacterial killing leukocyte, along with fibroblastic collagen production supporting angiogenesis [26,27]. Increase of oxygen within the infected bone leads to a state of hyperoxia which cancels the hypoxic state of the bone.…”

Section: Using the Hbot To Heal The Tibial Distal Osteomyelitis And S...mentioning

confidence: 99%

Application of Hyperbaric Oxygen Therapy in Chronic Distal Tibial Osteomyelitis in Severe Extremity Trauma

Slater

2023

J Regen Biol Med.

View full text Add to dashboard Cite

The purpose of this case study is to present the utility of using hyperbaric oxygen therapy (HBOT) as a tool to treat septic arthritis and tibial distal osteomyelitis. A 28-year-old female patient presented with septic arthritis and tibial distal osteomyelitis following an open complex ankle fracture due to a motor vehicle accident (MVA). The patient had internal fixation surgery, flap surgery and the debridement’s for infection. Osteomyelitis remains a troubling disorder to treat with catastrophic repercussion for the infected limb. The patient underwent 50 total HBOT sessions at 100 kPa using the integrant Hyperbaric mono chamber. This case study proves the viability of HBOT as an important adjunctive treatment for septic arthritis and osteomyelitis. It also shows that osteomyelitis can be reclaimed without necessity to remove it.

show abstract

Section: Using the Hbot To Heal The Tibial Distal Osteomyelitis And S...mentioning

confidence: 99%

Application of Hyperbaric Oxygen Therapy in Chronic Distal Tibial Osteomyelitis in Severe Extremity Trauma

Slater

2023

J Regen Biol Med.

View full text Add to dashboard Cite

show abstract

“…Hyperbaric oxygen therapy can be given in patients with chronic osteomyelitis associated with necrotizing soft tissue. Improved patient survival, better outcome and a decreased need for surgical intervention have been observed in patients treated with hyperbaric oxygen [31].…”

Section: Radiographic Featuresmentioning

confidence: 99%

Acute Osteomyelitis of the Mandible in a Geriatric Female Individual During Pandemic in India: A Case Report and Literature Review

Shunmugavelu¹

2022

Ukr. Dent. Alm.

View full text Add to dashboard Cite

A 75-year-old female patient reported to our hospital with pain and swelling on the left side of the face. Patient experienced severe throbbing pain a few days after extraction. Swelling developed 2 weeks after the extraction and progressively increased in size. Past dental history revealed that she had undergone extraction of lower left second molar 1 month back. Past medical history revealed that she was diabetic and hypertensive and was under medication for the same for the past 21 years. Patient had no history of jaw fracture and radiation exposure. Radiograph features showed cortical destruction and an increase in CRP level was observed through lab investigations. Radiograph revealed radiolucency with cortical bone destruction in relation to the lower left mandibular region. Laboratory investigations revealed an elevated CRP level and an increased albumin level in urine. Based on the history, clinical features, radiographic features and laboratory diagnosis a diagnosis of acute osteomyelitis was given. Incision and drainage were done followed by antibiotic therapy. The exposed bone was removed followed by curettage and irrigation. Patient was recalled after 10 days and exhibited no post-operative complications. This case was treated with antibiotic therapy and localized surgical management. The primary goal is treatment and or elimination of the causative factor followed by antibiotic therapy instituted according to antibiogram. Surgical therapy includes incision and drainage, jaw resection in invasive and extensive cases. Decortication, sequestrectomy and saucerization can also be done. Hyperbaric oxygen therapy can be given in patients with chronic osteomyelitis associated with necrotizing soft tissue. Improved patient survival, better outcome and a decreased need for surgical intervention have been observed in patients treated with hyperbaric oxygen. Osteomyelitis is a rare, invasive and destructive bacterial infection that can affect the quality of life. Further research in diagnosis criteria and techniques for management of osteomyelitis must be developed for better outcome and patient survival.

show abstract

“…Rarely do cases of PCO remain resistant to conventional treatments and require larger resection of bone with reconstruction. 3 , 4 …”

mentioning

confidence: 99%

Chronic Sclerosing Osteomyelitis of the Mandible Treated with Hemimandibulectomy and Fibular Free Flap Reconstruction

Singh

Graham

Bullock

et al. 2015

Plastic and Reconstructive Surgery - Global Open

View full text Add to dashboard Cite

Summary:Primary chronic osteomyelitis of the mandible is a rare condition that presents with a long-standing chronic facial swelling over the mandible, pain with mastication, and trismus. With no clinically appreciated acute phase, the aetiology often remains unknown. Many patients achieve adequate symptom control with broad-spectrum antibiotics, hyperbaric oxygen therapy and surgical debridement, or decortication of bone sequestration. However, because of the rarity of primary chronic osteomyelitis and the extensive involvement of the mandible that can result, we present a case of a 32-year-old woman with chronic disease of the left mandible requiring a left hemimandibulectomy and fibular free flap reconstruction. Few such cases have been reported in the literature, which require such extensive resection and reconstruction to control long-standing symptoms.

show abstract

Osteomyelitis Therapy – Hyperbaric Oxygen as an Adjunct in Treatment of Osteomyelitis of the Jaws

Cited by 4 publications

References 66 publications

Application of Hyperbaric Oxygen Therapy in Chronic Distal Tibial Osteomyelitis in Severe Extremity Trauma

Application of Hyperbaric Oxygen Therapy in Chronic Distal Tibial Osteomyelitis in Severe Extremity Trauma

Acute Osteomyelitis of the Mandible in a Geriatric Female Individual During Pandemic in India: A Case Report and Literature Review

Chronic Sclerosing Osteomyelitis of the Mandible Treated with Hemimandibulectomy and Fibular Free Flap Reconstruction

Contact Info

Product

Resources

About