Osteomyelitis

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doi:10.1097/01.idc.0000144910.19687.1f

Cited by 4 publications

(6 citation statements)

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“…A urine specimen is one of the most frequent specimens examined in many of the clinical-and hospital-based laboratories. Urine cultures account for up to 40% of those laboratories' cultures, making it the most common type of culture in such laboratories [27]. Urine is considered an ideal diagnostic specimen for its noninvasive, easy method of collection and the sufficient amount in which it is excreted [14].…”

Section: Urine Tests For Infectious Disease Diagnostics and Treatmentmentioning

confidence: 99%

“…A woman has a shorter urethra than a man does, which shortens the distance that bacteria must travel to reach the bladder [39].UTIs are generally categorized clinically as complicated and uncomplicated based on the presence of risk factors that comprise the urinary tract or the host defense [40]. Both Gram-negative and Gram-positive bacteria can cause UTIs, with Escherichia coli representing about 40-70% of the cases [27].…”

Section: Urinalysis For Diagnosis Of Urinary Tract Infectionmentioning

confidence: 99%

“…The diagnosis of UTIs is mainly based on urinalysis and the medical history of the patient, with latter being the most essential element [27].…”

Section: Urinalysis For Diagnosis Of Urinary Tract Infectionmentioning

confidence: 99%

“…Although methods such as suprapubic aspiration and straight catheter technique can reduce or even eliminate the chances of contamination, they are rarely performed as they are not practical for routine cases [27]. Importantly, these methods are invasive, costly, take a lot of time and effort, and are not risk free.…”

Section: Sample Collectionmentioning

confidence: 99%

“…[25,26]. The sensitivity and accuracy of urine test vary according to the agent being detected [14], and in some cases, urinalysis is only performed to exclude other diseases [27].…”

Section: Introductionmentioning

confidence: 99%

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Urine Tests for Diagnosis of Infectious Diseases and Antibiotic-Resistant Pathogens

Eltai¹,

Alhussain²,

Doiphode³

et al. 2020

Pathogenic Bacteria

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The relation between disease and urine was recognized by physicians since the earliest civilization BC. Urine is considered an ideal diagnostic specimen for its noninvasive and easy method of collection. Urinalysis encompasses a wide range of tests, which includes a variety of chemical tests, urine microscopy, bacterial cultures, and molecular tests. Importantly, urine tests can diagnose patients with antibiotic-resistant urinary tract infections (UTI), directly from urine and/or bacterial culture. This chapter summarizes the most common urine tests in the infectious disease field, with a special focus on diagnosing UTI and characterizing their antibiotic resistant. In addition to describing the advantages and limitation of these tests, the chapter explores the promising emerging technologies and methods in this field. This chapter is beneficial for scientists and healthcare workers in the field.

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Section: Urine Tests For Infectious Disease Diagnostics and Treatmentmentioning

confidence: 99%

Section: Urinalysis For Diagnosis Of Urinary Tract Infectionmentioning

confidence: 99%

“…The diagnosis of UTIs is mainly based on urinalysis and the medical history of the patient, with latter being the most essential element [27].…”

Section: Urinalysis For Diagnosis Of Urinary Tract Infectionmentioning

confidence: 99%

Section: Sample Collectionmentioning

confidence: 99%

“…[25,26]. The sensitivity and accuracy of urine test vary according to the agent being detected [14], and in some cases, urinalysis is only performed to exclude other diseases [27].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Urine Tests for Diagnosis of Infectious Diseases and Antibiotic-Resistant Pathogens

Eltai¹,

Alhussain²,

Doiphode³

et al. 2020

Pathogenic Bacteria

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Rapid Antimicrobial Susceptibility Testing of Patient Urine Samples Using Large Volume Free-Solution Light Scattering Microscopy

Yang

Zhang

et al. 2019

Anal. Chem.

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The emergence of antibiotic resistance has prompted the development of rapid antimicrobial susceptibility testing (AST) technologies that will enable evidence-based treatment and promote antimicrobial stewardship. To date, many rapid AST methods have been developed, but few are able to be performed on clinical samples directly. Here we developed a large volume light scattering microscopy technique that tracks phenotypic features of single bacterial cells directly in clinical urine samples without sample enrichment or culturing. The technique demonstrated rapid (90 min) detection of Escherichia coli in 24 clinical urine samples with 100% sensitivity and 83% specificity and rapid (90 min) AST in 12 urine samples with 87.5% categorical agreement with two antibiotics, ampicillin and ciprofloxacin.

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Specific Instantaneous Detection of Klebsiella pneumoniae for UTI Diagnosis with a Plasmonic Gold Nanoparticle Conjugated Aptasensor

Deb

Gogoi

Mandal

et al. 2023

ACS Appl. Bio Mater.

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Urinary tract infection (UTI), which can be caused by various pathogens, if not detected at an early stage can be fatal. It is essential to identify the specific pathogen responsible for UTI for appropriate treatment. This study describes a generic approach to the fabrication of a prototype for the noninvasive detection of a specific pathogen using a tailor-made plasmonic aptamer-gold nanoparticle (AuNP) assay. The assay is advantageous because the adsorbed specific aptamers passivate the nanoparticle surfaces and reduce and/or eliminate false-positive responses to nontarget analytes. Based on the localized surface plasmon resonance (LSPR) phenomena of AuNP, a point-of-care aptasensor was designed that shows specific changes in the absorbance in the visible spectra in the presence of a target pathogen for robust and fast screening of UTI samples. In this study, we demonstrate the specific detection of Klebsiella pneumoniae bacteria with LoD as low as 3.4 × 10 3 CFU/mL.

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Osteomyelitis

Cited by 4 publications

References 0 publications

Urine Tests for Diagnosis of Infectious Diseases and Antibiotic-Resistant Pathogens

Urine Tests for Diagnosis of Infectious Diseases and Antibiotic-Resistant Pathogens

Rapid Antimicrobial Susceptibility Testing of Patient Urine Samples Using Large Volume Free-Solution Light Scattering Microscopy

Specific Instantaneous Detection of Klebsiella pneumoniae for UTI Diagnosis with a Plasmonic Gold Nanoparticle Conjugated Aptasensor

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