Osteomyelitis, Osteoradionecrosis (ORN), and Medication-Related Osteonecrosis of the Jaws (MRONJ)

Kushner, George M.; Flint, Robert L.

doi:10.1007/978-3-030-91920-7_41

Cited by 4 publications

(14 citation statements)

References 34 publications

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“…Osteomyelitis is a progressive bone marrow inflammation that involves the cortical plates and periosteal tissues 4 and occurs more often in the mandible than the maxilla in alveolar osteomyelitis 5 . Osteomyelitis occurs as a result of trauma 6 , bone surgery 7 , vascular insufficiency 8 , or tooth extraction in general 9 and is often associated with dental implants 10 . Odontogenic causes are usually infections arising from a pulpal infection of a tooth or an infected gingival pocket as well as secondary infections after dental surgery 11 .…”

Section: Introductionmentioning

confidence: 99%

“…Numerous classification systems have been proposed to categorize osteomyelitis, including suppurative or non-suppurative, hematogenous, or resulting from a contiguous focus of infection 8 . Additionally, acute and chronic osteomyelitis are identified using unique International Classification of Diseases codes 12 .…”

Section: Introductionmentioning

confidence: 99%

“…Usually, this is a secondary process as the bacteria spread through adjacent soft tissues, extraction sites, or fracture sites to affect bone 26 . Therefore, infections without soft tissue involvement are particularly rare 8 .…”

Section: Introductionmentioning

confidence: 99%

“…Treatment of osteomyelitis of the jaws includes elimination of the cause, incision and drainage, sequestrectomy, saucerization, decortication, jaw resection, antibiotics, and hyperbaric oxygen 29 . Additionally, managing mandibular osteomyelitis may be challenging given its anatomic location and polymicrobial nature 30 and can lead to severe tooth and bone loss 8 , 30 . Alveolar bone resection and the resulting bone defects should be reconstructed since the presence of sufficient mandible bone is essential for successful dental rehabilitation 8 , 31 .…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, managing mandibular osteomyelitis may be challenging given its anatomic location and polymicrobial nature 30 and can lead to severe tooth and bone loss 8 , 30 . Alveolar bone resection and the resulting bone defects should be reconstructed since the presence of sufficient mandible bone is essential for successful dental rehabilitation 8 , 31 . Several methods of reconstruction are available for cases with continuity resection of the mandible owing to osteomyelitis of the jaws, including fibula free flap (FFF) 32 , 33 or deep circumflex iliac artery (DCIA) flap 34 .…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Can jaw bone healed from chronic sclerosing osteomyelitis be considered healthy when planning dental implants? Case report with 20-year follow-up

Grün,

Pfaffeneder-Mantai,

Schneider

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction and importance: Extraction of mandibular third molars can lead to complications such as chronic sclerosing osteomyelitis (CSO), an inflammatory bone marrow disease that tends to progress. CSO involves the cortical plates and often the periosteal tissues and is caused by a variety of microorganisms, including Corynebacterium spp. The treatment of CO and CSO remains challenging, as there is no universal treatment protocol. This case report investigated whether jaw bone that has healed from chronic sclerosing osteomyelitis can be considered healthy bone when planning dental implants. Case presentation: A 21-year-old Caucasian woman developed chronic osteomyelitis (CO) and CSO after third molar surgery. Clinical discussion: A combination of alveolar ridge bone resection, extraction of teeth 47–32, and long-term specific antibiotic therapy against Corynebacterium spp. was administered. An attempt at preprosthetic alveolar ridge reconstruction with an anterior superior iliac crest bone graft resulted in graft failure and the patient refused further harvesting procedures. Implantation in the intraforaminal zone also resulted in the loss of two implants after loading. Finally, inferior alveolar nerve transposition resulted in the successful reimplantation of two implants, which were fully functional almost 11 years later. Conclusion: This case report presents the treatment history of this patient. With a longitudinal observation period of >20 years, the results of this case demonstrate the successful treatment of bone with CO, CSO, and Corynebacterium spp. infection. Following the removal of infected bone, radical debridement, and long-term antibiotic therapy, bone health was restored.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Can jaw bone healed from chronic sclerosing osteomyelitis be considered healthy when planning dental implants? Case report with 20-year follow-up

Grün,

Pfaffeneder-Mantai,

Schneider

et al. 2024

Annals of Medicine &Amp; Surgery

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Mandibular reconstruction with TMJ prosthesis: management of osteomyelitis after orthognathic surgery (Case Report)

Leal,

Del Santo,

Mahboob

et al. 2023

Oral Maxillofac Surg

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This case report presents a rare case of osteomyelitis following bimaxillary orthognathic and geioplasty surgeries. The patient, a 41-year-old female, presented with facial pain, di culty in opening her mouth, and mandibular deviation four months after the initial orthognathic surgery. During the four months, the patient had experienced two post-operative complications that required surgical intervention.Examination revealed mobility between osteotomy segments of the right mandibular body, and Computer Tomographic scan analysis revealed osteomyelitis, and non-union of the right osteotomy side of the mandible from the previous surgery. Due to the advanced state of the disease and signi cant bone resorption, treatment was planned in two stages, involving bone debridement and then reconstruction with a custom made extended temporomandibular joint prosthesis. The patient had no postoperative complications and achieved satisfactory functional and aesthetic outcomes. This case emphasizes the

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Unusual Case of Management of Osteomyelitis after Orthognathic Surgery: Mandibular Reconstruction with TMJ Prosthesis

Leal

Santo

Nasim³

et al. 2023

Preprint

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This case report presents a rare case of osteomyelitis following bimaxillary orthognathic and geioplasty surgeries. The patient, a 41-year-old female, presented with facial pain, difficulty in opening her mouth, and mandibular deviation four months after the initial orthognathic surgery. During the four months, the patient had experienced two post-operative complications that required surgical intervention. Examination revealed mobility between osteotomy segments of the right mandibular body, and Computer Tomographic scan analysis revealed osteomyelitis, and non-union of the right osteotomy side of the mandible from the previous surgery. Due to the advanced state of the disease and significant bone resorption, treatment was planned in two stages, involving bone debridement and then reconstruction with a custom made extended temporomandibular joint prosthesis. The patient had no postoperative complications and achieved satisfactory functional and aesthetic outcomes. This case emphasizes the importance of careful monitoring and prompt management of postoperative complications following orthognathic surgery to prevent rare but serious complications such as osteomyelitis.

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Osteomyelitis, Osteoradionecrosis (ORN), and Medication-Related Osteonecrosis of the Jaws (MRONJ)

Cited by 4 publications

References 34 publications

Can jaw bone healed from chronic sclerosing osteomyelitis be considered healthy when planning dental implants? Case report with 20-year follow-up

Can jaw bone healed from chronic sclerosing osteomyelitis be considered healthy when planning dental implants? Case report with 20-year follow-up

Mandibular reconstruction with TMJ prosthesis: management of osteomyelitis after orthognathic surgery (Case Report)

Unusual Case of Management of Osteomyelitis after Orthognathic Surgery: Mandibular Reconstruction with TMJ Prosthesis

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