Tumors and Tumor-Like Lesions of Bone 2015
DOI: 10.1007/978-1-4471-6578-1_9
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Osteoid Osteoma

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Cited by 5 publications
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“…The typical clinical picture of the disease is pain that worsens at night, which may be alleviated by Non-Steroidal Anti Inflammatory Drugs (NSAIDs) [5] , [6] . OO is highly vascularized and innervated [7] , and the underlying cause of pain seems to be related to high prostaglandin levels (100–1000 × higher than normal), with prostaglandin E2 being the main subtype. In addition, these prostaglandins are responsible for vasodilatation and edema formation in the surrounding bone marrow and soft tissues [5] , [6] .…”
Section: Introductionmentioning
confidence: 99%
“…The typical clinical picture of the disease is pain that worsens at night, which may be alleviated by Non-Steroidal Anti Inflammatory Drugs (NSAIDs) [5] , [6] . OO is highly vascularized and innervated [7] , and the underlying cause of pain seems to be related to high prostaglandin levels (100–1000 × higher than normal), with prostaglandin E2 being the main subtype. In addition, these prostaglandins are responsible for vasodilatation and edema formation in the surrounding bone marrow and soft tissues [5] , [6] .…”
Section: Introductionmentioning
confidence: 99%