Osteoclastoma of occipital bone

Sharma, Vishal; Newton, Goodwin

doi:10.3349/ymj.1991.32.2.169

Cited by 8 publications

(8 citation statements)

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“…The site and condition involving both endochondral and intramembranous ossification are exceedingly rare. In the English language literature, only four case reports of GCT of the occipital bone have been published [6,[9][10][11] but no case report describing GCT involving endochondral and intramembranous ossification exists. Thus, GCT occurrence in intramembranous ossification remains largely unexplained.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, GCT occurrence in intramembranous ossification remains largely unexplained. Many hypotheses have been postulated including the presence of aberrant cells and the occurrence of metaplasia at local primitive connective tissue [6].…”

Section: Discussionmentioning

confidence: 99%

“…GCT of bone is an uncommon primary bone neoplasm, which typically occurs at the epiphyses of long bones and rarely manifests in the skull. GCTs of the cranium represent only 1% of all GCTs and preferentially affect the sphenoid and temporal bones [1][2][3][4][5][6]. Primary GCTs of the posterior cranial fossa are exceedingly rare.…”

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confidence: 99%

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Giant cell tumour of the posterior cranial fossa: a case report

Yao²

2011

BJR

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Giant cell tumours (GCTs) of the cranium preferentially affect the sphenoid and temporal bones. We report a 19-year-old patient with GCT involving the left occipital bone and petromastoid portion of the temporal bone. CT and MRI revealed a predominantly expansive soft-tissue mass of the posterior cranial fossa. The patient underwent surgery. Permanent histopathological sections and immunostatins revealed the presence of a GCT. The radiological features and method of surgical intervention of this rare lesion are discussed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Giant cell tumour of the posterior cranial fossa: a case report

Yao²

2011

BJR

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“…11 Surgical excision is the preferred treatment for giant cell tumors of the skull. 2,26,33,37,38 Local recurrence rates and prognosis both correlate with the extent of resection. Giant cell tumors are considered locally aggressive and may recur at or near the site of resection.…”

Section: Discussionmentioning

confidence: 99%

Giant cell tumor of the skull in pediatric patients

Elder¹,

Berry²,

González-Gómez³

et al. 2007

Journal of Neurosurgery: Pediatrics

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Giant cell tumors of the bone are rare, locally aggressive lesions that primarily affect the epiphyses of long bones. These tumors can occur in the skull, principally in the sphenoid and temporal bones. Symptoms of these tumors depend on their site of origin but typically include headache, pain, visual field defects, and conductive hearing loss. Histologically, these tumors consist of three cell types: osteoclast-like multinucleated giant cells; round mononuclear cells resembling monocytes; and spindle-shaped, fibroblast-like stromal cells. Radiographically, the tumors appear osteolytic and radiolucent without a sclerotic border. These tumors typically present in the third to fourth decades of life and rarely occur in patients under 20 years of age. The small number of studies of giant cell tumors of the skull has focused on the adolescent and adult populations. The authors report two cases of giant cell tumors of the skull in pediatric patients. In the first case, a 2-year-old girl presented with swelling behind the right ear. In the second case, a 7-week-old girl presented with a mass within the external auditory canal. Both patients underwent metastatic workup and biopsy procedures before resection of the tumor. Both case reports contribute to the literature of giant cell tumors of the skull by describing this condition in pediatric patients. To the authors' knowledge, these cases represent the youngest two patients with giant cell tumors of the skull yet described.

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“…In the skull these tumours are very rare and have been reported in the temporal, sphenoid, petrous and occipital bones. [2][3][4] In the present article we present a young patient with primary giant cell tumour of the left temporal bone. A 14-year-old boy presented with a progressively increasing mass in the left temporal region of 8 months duration.…”

Section: Introductionmentioning

confidence: 93%