Osteochondritis dissecans of the weight-bearing surface of the medial femoral condyle in adults

Jaberi, Fereidoon Mojtahed

doi:10.1016/s0968-0160(02)00020-0

Cited by 14 publications

(14 citation statements)

References 22 publications

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“…Similarly, we were unable to demonstrate any relationship between lesion size and clinical outcome as has been previously described. 10, 28, 29 Outcome data on more patients are necessary to determine the influence of lesion size and location on clinical outcome.…”

Section: Discussionmentioning

confidence: 99%

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Does Operative Fixation of an Osteochondritis Dissecans Loose Body Result in Healing and Long-Term Maintenance of Knee Function?

2009

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Background Osteochondritis dissecans (OCD) can progress to loose body formation resulting in a Grade IV defect. The decision to fix versus excise the loose body is controversial. Published operative fixation outcomes are small case series with short follow-up. Hypothesis Operative fixation (ORIF) of the loose body into the grade IV defect will heal and approximate “normal” knee function at long-term follow-up. Study Design Case series Methods Twelve patients were identified who underwent ORIF of a knee OCD loose body into the Grade IV osteochondral defects ranging in size from 2.0 to 8.0 cm2 (mean 3.5 cm2). After 12 weeks, hardware was removed and healing was assessed. Long-term outcomes were assessed with a Knee injury and Osteoarthritis Outcome Score (KOOS) and a Marx activity score. Results Arthroscopy for screw removal revealed stable healing in 92% (11/12) of patients. No patients required subsequent surgery for a loose body. At an average of 9.2 years follow-up (range 3.8-15.8 years) 83 % (10/12) of patients completed the KOOS. KOOS subscale scores for pain (mean 87.8, range 67-100), other symptoms (mean 81.8, range 61-96), function in activities of daily living (mean 93.1, range 72-100), and sports and recreation function (mean 74.0, range 40-100) were not significantly lower than published age matched controls. However the KOOS subscale for knee related quality of life (mean 61.9, range 31-88) was significantly lower (p = 0.003). Conclusions Operative fixation of Grade IV OCD loose bodies results in stable fixation. At an average 9 years after surgery, patients did not have symptoms of osteoarthritis pain and had normal function in activities of daily life. However, patients reported significantly lower knee related quality of life. Operative fixation of OCD loose bodies is a better alternative to lesion excision.

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Section: Discussionmentioning

confidence: 99%

“…12, 20, 29, 60 Reported healing rates by radiograph have been between 80 and 100% with good to excellent clinical outcomes in the majority of patients. 1, 13, 16, 21, 28, 30, 34, 40, 43, 44, 48, 54 …”

Section: Introductionmentioning

confidence: 99%

Does Operative Fixation of an Osteochondritis Dissecans Loose Body Result in Healing and Long-Term Maintenance of Knee Function?

2009

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“…The disease occurs at the physes of long bones, in the talus, and most commonly in the knee, particularly the medial femoral condyle [9,12,16]. Diagnosis is generally possible with conventional radiographs, but surgical treatment is best guided by proper staging via MRI [7].…”

Section: Introductionmentioning

confidence: 99%

Case Report: Osteochondritis Dissecans in Twins

Mackie

Wilkins

2010

Clinical Orthopaedics &Amp; Related Research

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Osteochondritis dissecans is a lesion of subchondral bone with subsequent involvement of the overlying cartilage. Although the etiology of the disease is unknown, mechanical, traumatic, and ischemic etiologies have been suggested, in addition to developmental and genetic factors. There are several treatment options depending on the stage of the disease and surgeon preference. The use of a fresh osteochondral allograft for treatment of a lesion of the femoral condyle is relatively new, and we report its use in a unique situation involving identical twins who both presented with osteochondritis dissecans of the same anatomic location within 2 years of each other. Since these were identical lesions in identical twins, this commonality supports the suggestion that some genetic component may be present in the etiology, especially in this situation where a genetic connection existed. We recommend genetic studies to determine the extent of genetic influence on the disease.

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“…Este patrón se sugiere para todas las articulaciones, como lo demuestran numerosos estudios clínicos de rodilla (Desai et al 1987;Jaberi 2002;Uematsu et al 2005), del codo (Brownlow et al 2006), del tobillo (Ming et al 2004) Por otra parte, no existe consenso acerca de los efectos de la edad en la prevalencia de la OCD, aunque esta patología parece influir en mayor medida a individuos que transitan las primeras etapas de la vida. La forma juvenil se presenta en niños y adolescentes entre 5 y 15 años de edad (Schenck y Goodnight 1996), la cual se asocia con el crecimiento y desarrollo óseo epifisial y con microtraumas repetitivos (e.g.…”

Section: Terminología Patogénesis Y Epidemiología General De La Ocdunclassified

Osteocondritis disecante. Primeros resultados en restos humanos de cazadores-recolectores del Holoceno en Patagonia austral

et al. 2018

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RMA Osteocondritis disecante. Primeros resultados en restos humanos de cazadores-recolectores del Holoceno en Patagonia australLa osteocondritis disecante (OCD) es una condición caracterizada por la separación localizada de un fragmento del cartílago articular y el hueso subcondral, que afecta a las epífisis articulares de humanos y otros mamíferos (e.g. perros, gatos, cerdos, ratas, caballos, entre otros) (Edmonds y Heyworth 2014; Schenck y Goodnight 1996). Ha sido comúnmente estudiada en bioarqueología como un indicador asociado con la actividad física, aunque otros componentes etiológicos pueden estar involucrados (e.g. factores genéticos-hereditarios, variaciones anatómicas de las articulaciones, isquemia del cartílago durante el crecimiento o la vejez de un individuo; Bulgheroni et al. 2017;Bullough 2004;Ytrehus et al. 2007).En Argentina, son escasas las investigaciones paleopatológicas que han considerado el análisis de la OCD en restos humanos, las cuales en general consistieron en relevamientos descriptivos de lesiones en individuos

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Osteochondritis dissecans of the weight-bearing surface of the medial femoral condyle in adults

Cited by 14 publications

References 22 publications

Does Operative Fixation of an Osteochondritis Dissecans Loose Body Result in Healing and Long-Term Maintenance of Knee Function?

Does Operative Fixation of an Osteochondritis Dissecans Loose Body Result in Healing and Long-Term Maintenance of Knee Function?

Case Report: Osteochondritis Dissecans in Twins

Osteocondritis disecante. Primeros resultados en restos humanos de cazadores-recolectores del Holoceno en Patagonia austral

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