Osteoblast behavior on polytetrafluoroethylene modified by long pulse, high frequency oxygen plasma immersion ion implantation

Wang, Huaiyu; Kwok, Dixon T. K.; Wang, Wei; Wu, Zhengwei; Tong, Liping; Zhang, Yumei; Chu, Paul K.

doi:10.1016/j.biomaterials.2009.09.066

Cited by 71 publications

(35 citation statements)

References 38 publications

(38 reference statements)

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“…Some authors reported higher cell affinity to rough surfaces [23,[46][47][48][49] and others the opposite [25,26,42,48]. In general, only a few cells can adhere on superhydrophobic surfaces, therefore decreasing their proliferative capacity [26,42].…”

Section: Cell Viability Adhesion and Proliferationmentioning

confidence: 99%

“…In general, only a few cells can adhere on superhydrophobic surfaces, therefore decreasing their proliferative capacity [26,42]. In contrast, some studies have shown cell proliferation and survival [46,48] and in some cases even differentiation [47] and enhanced transfection efficiency [49]. But one also has to keep in mind that cell behavior can be cell type dependent [23,29].…”

Section: Cell Viability Adhesion and Proliferationmentioning

confidence: 99%

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Wettability Influences Cell Behavior on Superhydrophobic Surfaces with Different Topographies

et al. 2012

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Surface wettability and topography are recognized as critical factors influencing cell behavior on biomaterials. So far only few works have reported cell responses on surfaces exhibiting extreme wettability in combination with surface topography. The goal of this work is to study whether cell behavior on superhydrophobic surfaces is influenced by surface topography and polymer type. Biomimetic superhydrophobic rough surfaces of polystyrene and poly(l-lactic acid) with different micro/nanotopographies were obtained from smooth surfaces using a simple phase-separation based method. Total protein was quantified and showed a less adsorption of bovine serum albumin onto rough surfaces as compared to smooth surfaces of the same material. The mouse osteoblastic MC3T3-E1 cell line and primary bovine articular chondrocytes were used to study cell attachment and proliferation. Cells attached and proliferate better in the smooth surfaces. The superhydrophobic surfaces allowed cells to adhere but inhibited their proliferation. This study indicates that surface wettability, rather than polymer type or the topography of the superhydrophobic surfaces, is a critical factor in determining cell behavior.

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Section: Cell Viability Adhesion and Proliferationmentioning

confidence: 99%

Section: Cell Viability Adhesion and Proliferationmentioning

confidence: 99%

Wettability Influences Cell Behavior on Superhydrophobic Surfaces with Different Topographies

et al. 2012

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“…Wang et al 15) used experiments with rat calvaria-derived osteoblasts adhered to polymer composites with different surface treatments to indicate that cell adsorption depends on the critical value of surface energy; if surface energy is above a threshold energy, cells will extend on the surface. With an increase in the surface polar component, cellular number, morphology, and ALP activity increase correspondingly; therefore, the effect of the polar component on osteoblasts on a titanium surface is larger than that of the diffusion component.…”

Section: Morphological Observationmentioning

confidence: 99%

Biocompatibility Evaluation of Titanium Produced by Laser Rapid Forming

Zhu

Tian

Xiao

et al. 2016

J. Hard Tissue Biology.

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The study aims to evaluate the biocompatibility of titanium produced by laser rapid forming. Ten laser rapid forming titanium (LRF Ti) discs and ten commercially pure titanium (CP Ti) discs were prepared; CP Ti discs were used as controls. Total surface energy was calculated by measuring the contact angle of the metallic surface, and calvaria of newborn Sprague-Dawley rats were used for the primary culture of osteoblasts to study adhesion, spreading, and proliferation of osteoblasts on the metallic surface. The dispersive component, polar component, and total surface energy of LRF Ti discs were larger than those of controls (P < 0.05). After 10 d of osteoblast culture, the cellular adhesive percentage and alkaline phosphatase activity of the LRF Ti group was significantly higher than those of controls (P < 0.05). With increasing culture time, more cells gradually attached to the LRF Ti metallic surface, which caused changes in cellular morphology. This study demonstrates that LRF Ti is highly compatible with bone similar to CP Ti and meets the biocompatibility requirements for implant materials.

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“…13 The second method employs high-energy sources including plasma, irradiation, and corona to activate the Teflon surface. 15,16 For example, Chu et al adopted plasma treatment to change both the morphological and chemical structures of PTFE surface on which osteoblast 17 and mesenchymal stem cell 18 behaviors were well tailored. In addition, Lee et al conducted sensitive DNA detections on functionalized FEP substrate by treating the inert surface with ion implantation and graft polymerization.…”

Section: Introductionmentioning

confidence: 99%

Convenient surface functionalization of whole-Teflon chips with polydopamine coating

Shen

Xiong

2015

Biomicrofluidics

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This paper presents a convenient strategy to modify the surface of whole-Teflon microfluidic chips by coating the channel walls with a thin layer of polydopamine (PDA) film, which is formed by oxidation-induced self-polymerization of dopamine in alkaline solution. Two coating strategies, static incubation and dynamic flow, are demonstrated and used for tuning the physical and chemical properties of the coated channel walls. The functionalized surfaces were investigated with the contact angle, X-ray photoelectron spectroscopy, and atomic force microscopy measurements. The coating time was optimized according to the fluorescent intensity of the green fluorescent protein immobilized on the modified surface. Applications of the PDA-modified Teflon microchips in bioanalysis were demonstrated with a typical sandwich immunoassay. Moreover, long-term cell culture experiments on modified and native Teflon chips revealed that the chip biocompatibility can be greatly improved with PDA coating. The results indicate that the surface properties of the Teflon can be easily controlled by the PDA modification, thus greatly expanding the application scope of whole-Teflon chips for various chemical and biological research fields. V C 2015 AIP Publishing LLC.

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Osteoblast behavior on polytetrafluoroethylene modified by long pulse, high frequency oxygen plasma immersion ion implantation

Cited by 71 publications

References 38 publications

Wettability Influences Cell Behavior on Superhydrophobic Surfaces with Different Topographies

Wettability Influences Cell Behavior on Superhydrophobic Surfaces with Different Topographies

Biocompatibility Evaluation of Titanium Produced by Laser Rapid Forming

Convenient surface functionalization of whole-Teflon chips with polydopamine coating

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