Osteoarthritis year 2012 in review: imaging

Roemer, Frank W.; Guermazi, Ali

doi:10.1016/j.joca.2012.07.008

Cited by 19 publications

(11 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…14,19 An osteoarthritic joint is characterized by degenerative changes, such as articular cartilage loss, subchondral bone thickening, and osteophyte formation. [22][23][24][25][26] The primary morphologic changes include thinning, fissuring, and fragmentation of articular cartilage. With progression of the disease comes a continuous loss of articular cartilage, accompanied with a decrease of collagen type-II and aggrecan, 27,28 leading to exposure of subchondral bone.…”

Section: Anatomy Of Cartilage and Subchondral Bonementioning

confidence: 99%

Osteochondral Tissue Engineering with Biphasic Scaffold: Current Strategies and Techniques

Shimomura

Moriguchi²,

Murawski³

et al. 2014

Tissue Engineering Part B: Reviews

113

View full text Add to dashboard Cite

The management of osteoarthritis (OA) remains challenging and controversial. Although several clinical options exist for the treatment of OA, regeneration of the damaged articular cartilage has proved difficult due to the limited healing capacity. With the advancements in tissue engineering and cell-based technologies over the past decade, new therapeutic options for patients with osteochondral lesions potentially exist. This review will focus on the feasibility of tissue-engineered biphasic scaffolds, which can mimic the native osteochondral complex, for osteochondral repair and highlight the recent development of these techniques toward tissue regeneration. Moreover, basic anatomy, strategy for osteochondral repair, the design and fabrication methods of scaffolds, as well as the choice of cells, growth factor, and materials will be discussed. Specifically, we focus on the latest preclinical animal studies using large animals and clinical trials with high clinical relevance. In turn, this will facilitate an understanding of the latest trends in osteochondral repair and contribute to the future application of such clinical therapies in patients with OA.

show abstract

Section: Anatomy Of Cartilage and Subchondral Bonementioning

confidence: 99%

Osteochondral Tissue Engineering with Biphasic Scaffold: Current Strategies and Techniques

Shimomura

Moriguchi²,

Murawski³

et al. 2014

Tissue Engineering Part B: Reviews

113

View full text Add to dashboard Cite

show abstract

“…Dans la pratique clinique, la radiographie standard demeure l'examen de première ligne pour l'évaluation et le suivi de l'arthrose [76] . Cette technique d'imagerie est largement disponible et peu irradiante .…”

Section: Sémiologie Radiographique Généraleunclassified

Arthrose

Henrotin¹,

Alvarez-Miezentseva²,

Simoni³

2013

Imagerie Musculosquelettique : Pathologies Générales

View full text Add to dashboard Cite

“…Other methods include magnetic resonance imaging (MRI) [14, 15] and self-reporting [10]. Knee, hand, and hip OA are also assessed using the American College of Rheumatology (ACR) clinical criteria [16–18].…”

Section: Introductionmentioning

confidence: 99%

Validation of Administrative Osteoarthritis Diagnosis Using a Clinical and Radiological Population-Based Cohort

Rahman

Kopeć

Goldsmith

et al. 2016

International Journal of Rheumatology

View full text Add to dashboard Cite

Objectives. The validity of administrative osteoarthritis (OA) diagnosis in British Columbia, Canada, was examined against X-rays, magnetic resonance imaging (MRI), self-report, and the American College of Rheumatology criteria. Methods. During 2002–2005, 171 randomly selected subjects with knee pain aged 40–79 years underwent clinical assessment for OA in the knee, hip, and hands. Their administrative health records were linked during 1991–2004, in which OA was defined in two ways: (AOA1) at least one physician's diagnosis or hospital admission and (AOA2) at least two physician's diagnoses in two years or one hospital admission. Sensitivity, specificity, and predictive values were compared using four reference standards. Results. The mean age was 59 years and 51% were men. The proportion of OA varied from 56.3 to 89.7% among men and 77.4 to 96.4% among women according to reference standards. Sensitivity and specificity varied from 21 to 57% and 75 to 100%, respectively, and PPVs varied from 82 to 100%. For MRI assessment, the PPV of AOA2 was 100%. Higher sensitivity was observed in AOA1 than AOA2 and the reverse was true for specificity and PPV. Conclusions. The validity of administrative OA in British Columbia varied due to case definitions and reference standards. AOA2 is more suitable for identifying OA cases for research using this Canadian database.

show abstract

Osteoarthritis year 2012 in review: imaging

Cited by 19 publications

References 47 publications

Osteochondral Tissue Engineering with Biphasic Scaffold: Current Strategies and Techniques

Osteochondral Tissue Engineering with Biphasic Scaffold: Current Strategies and Techniques

Arthrose

Validation of Administrative Osteoarthritis Diagnosis Using a Clinical and Radiological Population-Based Cohort

Contact Info

Product

Resources

About