Osteoarthritis in the cat

Abstract

There are several publications that show that meloxicam is an effective NSAID for the cat and can be used long-term. It is easy to administer and there is published evidence that meloxicam can actually slow the progression of CKD in this species. Many other drugs are used to treat chronic pain in the cat but there is no documented evidence of their efficacy in OA. Unlike the dog, there is limited evidence for the effectiveness of omega-3 fatty acid-rich diets in managing feline OA and further work is required. There is no published data as yet for the usefulness or otherwise of nutraceuticals (glucosamine and chondroitin) in managing feline OA; studies in the authors' clinic suggest some pain-relieving effect. Research into environmental enrichment as a way of improving quality of life in cats with painful OA is lacking, but it is an approach worth using where possible. Modifications to the environment (eg, provision of comfortable bedding and ramps) are also important.

Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups and in cats recruited for degenerative joint disease studies

“…This has important implications for treatment 35. Avoiding NSAIDs in cats with both DJD and CKD would mean few cats with DJD would be treated with what is currently assumed to be the most effective class of analgesics for the treatment of chronic musculoskeletal pain in the cat.…”

Scottish Fold Kedilerde Kalıtsal Osteokondrodisplazi

“…Pentosan polysulfate [12] and chondroitin sulfate [6] have been recommended for cats affected by the disease. Furthermore, in cases accompanied by pain due to arthritis, meloxicam is a non-steriodal anti-inflammatory drug recommended for its safe long-term use [6,13] . In another study, the minimally invasive technique of radiotherapy was applied for its prevention of excessive bone formation and suppression of the inflammatory process [5,14] .…”

Papel Da Nutrição Na Doença Articular Degenerativa Do Esqueleto Apendicular De Gatos

“…Neste sentido será abordada conjuntamente a osteoartrite, um tipo específico de doença articular degenerativa (9). Trata-se de doença progressiva complexa, que afeta a articulação sinovial diartrodial, caracterizada por dor articular, rigidez e limitação do movimento, que pode ser de causa primária ou idiopática, ou secundária (congênita ou de desenvolvimento; traumática) (1, 9,10,11). Embora a osteoartrite seja categorizada como doença articular não inflamatória, há uma inflamação de baixo grau que tem papel importante na patogênese da afecção (11).…”

“…Notam-se ainda divergências entre estudos com relação às articulações apendiculares mais afetadas pela doença. Por exemplo, em pesquisa envolvendo um grupo de 38 casos, as articulações mais afetadas foram o cotovelo, seguida pela articulação coxofemoral (9). Em outro estudo populacional com 100 gatos, as articulações mais comprometidas foram a coxofemoral, seguida pelo joelho, tarso e finalmente o cotovelo (2).…”