Osteo-chondritis dissecans

Fairbank, H. A. T.

doi:10.1002/bjs.1800218108

Cited by 140 publications

(50 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 1933, Fairbanks [19] proposed traumatic contact between the lateral aspect of the medial femoral condyle and the tibial spine as the cause of OCD. However, Fairbank's theory would only explain OCD lesions in the lateral aspect of the medial femoral condyle.…”

Section: Etiologymentioning

confidence: 99%

A Review of Knowledge in Osteochondritis Dissecans: 123 Years of Minimal Evolution from König to the ROCK Study Group

Edmonds

Polousky

2013

Clinical Orthopaedics &Amp; Related Research

210

223

View full text Add to dashboard Cite

Background Osteochondritis dissecans (OCD) was first described to provide an explanation for the nontraumatic development of loose bodies within a joint. Despite many reports on the subject, there remains no clear understanding of the etiology, natural history, or treatment. Questions/purposes This review was undertaken to delineate (1) the etiology of OCD; (2) the presentation and locations; (3) the most appropriate imaging modalities; and (4) the most effective treatment strategies. Methods We reviewed the English literature using a database compiled from a Medline search for ''osteochondritis dissecans''. We identified 1716 publications, 1246 of which were in English. After exclusions, we reviewed 748 articles and of these cited 85. The observations of each study were then synthesized into this report. Results There appears to be no consensus concerning the etiology of OCD lesions. The presentations and locations are variable, but the knee, ankle, and elbow are most commonly involved. Although plain film assessment is important in OCD, there appears to be a trend toward the use of MRI, but the preferred sequences are in evolution. We found no consensus on the treatment of these lesions, related in part to the lack of agreement of methods for assessing outcomes. Conclusions Despite more than a century of study, we have made little advancement in our understanding of OCD. A study group has been formed to address this issue and actively seeks to answer these unknown issues regarding OCD.

show abstract

Section: Etiologymentioning

confidence: 99%

A Review of Knowledge in Osteochondritis Dissecans: 123 Years of Minimal Evolution from König to the ROCK Study Group

Edmonds

Polousky

2013

Clinical Orthopaedics &Amp; Related Research

210

223

View full text Add to dashboard Cite

show abstract

“…Although the etiology of OCD has not fully been elucidated, it is commonly accepted that repetitive micro-trauma may play a significant role in the development of this disorder [3][4][5][6][7]12,21]. One hypothesis for a traumatic incident causing an OCD involves the tibial eminence causing a direct contusion on the medial femoral condyle [6].…”

Section: Discussionmentioning

confidence: 99%

“…Fairbank proposed repetitive micro-trauma of the tibial spine onto the lateral aspect of the medial femoral condyle as a potential cause [6]. Trauma, both acute and repetitive events, as well as genetic factors may play a role in the development of this condition [4,7].…”

Section: Introductionmentioning

confidence: 99%

Osteochondritis dissecans development after bone contusion of the knee in the skeletally immature: a case series

Shea

Jacobs²,

Grimm

et al. 2012

Knee Surg Sports Traumatol Arthrosc

View full text Add to dashboard Cite

Osteochondritis dissecans (OCD) is thought to be an acquired osteochondral disorder, and its etiology may be multi-factorial. Trauma, both acute and repetitive events, has previously been proposed as a potential cause for OCD development. We present two cases of skeletally immature males who developed a symptomatic OCD lesion following a femoral condyle bone contusion. These cases suggest that an acute traumatic event may lead to the development of OCD of the knee.

show abstract

“…Ischemia has also been proposed as a cause of OCD [3,5,14], although whether this is a primary cause, a secondary effect of trauma, or other pathophysiology is unclear. Fairbank's [6] theory, later advocated by Smillie [24], was that repetitive microtrauma caused OCD of the knee. Trauma, either acute or repetitive microtrauma, has become a more accepted cause of OCD as a result of the high incidence of this disorder in the athletic population [2,4,6,7,10,13,14,16,28].…”

Section: Introductionmentioning

confidence: 99%

Osteochondritis Dissecans Knee Histology Studies Have Variable Findings and Theories of Etiology

Shea

Jacobs

Carey

et al. 2013

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

Background Although many etiological theories have been proposed for osteochondritis dissecans (OCD), its etiology remains unclear. Histological analysis of the articular cartilage and subchondral bone tissues of OCD lesions can provide useful information about the cellular changes and progression of OCD. Previous research is predominantly comprised of retrospective clinical studies from which limited conclusions can be drawn. Questions/purposes The purposes of this study were threefold: (1) Is osteonecrosis a consistent finding in OCD biopsy specimens? (2) Is normal articular cartilage a consistent finding in OCD biopsy specimens? (3) Do histological studies propose an etiology for OCD based on the tissue findings? Methods We searched the PubMed, Embase, and CI-NAHL databases for studies that conducted histological analyses of OCD lesions of the knee and identified 1560 articles. Of these, 11 met our inclusion criteria: a study of OCD lesions about the knee, published in the English language, and performed a histological analysis of subchondral bone and articular cartilage. These 11 studies were assessed for an etiology proposed in the study based on the study findings. Results Seven of 11 studies reported subchondral bone necrosis. Four studies reported normal articular cartilage, two studies reported degenerated or irregular articular cartilage, and five studies found a combination of normal and degenerated or irregular articular cartilage. Five studies proposed trauma or repetitive stress and two studies proposed poor blood supply as possible etiologies. Conclusions We found limited research on histological analysis of OCD lesions of the knee. Future studies with consistent methodology are necessary to draw major conclusions about the histology and progression of OCD lesions. Inconsistent histologic findings have resulted in a lack of consensus regarding the presence of osteonecrosis, whether the necrosis is primary or secondary, the association of cartilage degeneration, and the etiology of OCD. Such studies could use a standardized grading system to allow better comparison of findings.

show abstract

Osteo-chondritis dissecans

Cited by 140 publications

References 9 publications

A Review of Knowledge in Osteochondritis Dissecans: 123 Years of Minimal Evolution from König to the ROCK Study Group

A Review of Knowledge in Osteochondritis Dissecans: 123 Years of Minimal Evolution from König to the ROCK Study Group

Osteochondritis dissecans development after bone contusion of the knee in the skeletally immature: a case series

Osteochondritis Dissecans Knee Histology Studies Have Variable Findings and Theories of Etiology

Contact Info

Product

Resources

About