“…The two other variants, the juvenile trabecular and the juvenile psammatoid ossifying fibroma (JTOF and JPOF), are classified as bone tumours and can also occur in bones other than the mandible or maxilla (Baumhoer, ; El Mofty, ; Zegalie et al, ). In fact, JPOF is more often found in areas other than the jawbones, especially in the sinusoid walls, most frequently affects patients between the second and fourth decades of life, and is somewhat more prevalent in men than in women (Baumhoer, ; Zegalie et al, ). Psammatoid matrix mineralisations characteristic of JPOF were not identified in this case, and one would also expect to find expansion of the sinusoid wall, which was not the case here.…”
In the bioarchaeological analysis of burials from a medieval graveyard at Hettstedt, Central Germany, a male skeleton of about 40 to 50 years at death with an unusual bony structure in the left maxillary sinus was discovered. Macroscopic examination exhibited a balloon‐shaped osseous lesion with solid cortical surface 2.5 × 1.5 cm in size. Micro‐CT scans revealed trabecular structures around a central cavity. The margins of the osseous lesion were well defined without infiltration of normal maxillary bone tissue. The histopathological analysis showed the presence of lamellar and woven bone. The structure and localisation of the tumour‐like lesion suggest that the formation was the result of chronic inflammation and that chronic dental sinusitis seems to have triggered a large reactive ossification.
“…The two other variants, the juvenile trabecular and the juvenile psammatoid ossifying fibroma (JTOF and JPOF), are classified as bone tumours and can also occur in bones other than the mandible or maxilla (Baumhoer, ; El Mofty, ; Zegalie et al, ). In fact, JPOF is more often found in areas other than the jawbones, especially in the sinusoid walls, most frequently affects patients between the second and fourth decades of life, and is somewhat more prevalent in men than in women (Baumhoer, ; Zegalie et al, ). Psammatoid matrix mineralisations characteristic of JPOF were not identified in this case, and one would also expect to find expansion of the sinusoid wall, which was not the case here.…”
In the bioarchaeological analysis of burials from a medieval graveyard at Hettstedt, Central Germany, a male skeleton of about 40 to 50 years at death with an unusual bony structure in the left maxillary sinus was discovered. Macroscopic examination exhibited a balloon‐shaped osseous lesion with solid cortical surface 2.5 × 1.5 cm in size. Micro‐CT scans revealed trabecular structures around a central cavity. The margins of the osseous lesion were well defined without infiltration of normal maxillary bone tissue. The histopathological analysis showed the presence of lamellar and woven bone. The structure and localisation of the tumour‐like lesion suggest that the formation was the result of chronic inflammation and that chronic dental sinusitis seems to have triggered a large reactive ossification.
“…In contrast, sporadic ossifying fibromas of the jaw are rare and typically occur in an older age group [4]. Ossifying fibromas of the jaw arise from the mesenchymal cells of the periodontal ligament, the fibrous connective tissue found within the periodontal space, which secures the tooth [5].…”
Section: Introductionmentioning
confidence: 99%
“…The fibrous component of the tumour enhances following administration of contrast [6]. Ossifying fibromas typically do not cause root absorption, which is a feature of more aggressive lesions such as ameloblastomas, and unlike radicular or dentigerous cysts, there is no association with unerupted teeth [4]. Fig.…”
Section: Introductionmentioning
confidence: 99%
“…Fibrous dysplasia produces ill-defined bony expansion and has a characteristic ‘ground glass’ appearance, but it can be indistinguishable from an ossifying fibroma on imaging (Fig. 6) underlining the importance of multidisciplinary team discussion in making the diagnosis of an ossifying fibroma, and the need to review and correlate clinical, imaging and histopathological evidence [4]. As with ossifying fibromas of HPT-JT, Brown tumours may also appear on imaging as lucent jaw lesions with evidence of hyperparathyroid bone disease in the surrounding bone [7].…”
Section: Introductionmentioning
confidence: 99%
“…However, they demonstrate locally invasive features, e.g., they may splay the teeth [4]. They are expansile and can cause facial asymmetry.…”
Hyperparathyroidism jaw tumour syndrome is a rare autosomal dominant inherited endocrine neoplasia syndrome, which predisposes carriers to develop a triad of multiple ossifying fibromas of the maxilla and mandible, parathyroid adenomas and carcinomas (with consequent hyperparathyroidism) as well as renal and uterine tumours. The prevalence of this condition is unknown. Patients typically present initially with symptoms and signs of a jaw tumour. A high index of suspicion is required for the underlying diagnosis to be recognised, enabling appropriate management of jaw lesions, treatment of hyperparathyroidism, if present, as well as early detection of malignant disease and screening of family members.Teaching points• HPT-JT is a rare autosomal dominant inherited endocrine neoplasia syndrome.• HPT-JT causes facial disfigurement, morbidity secondary to hyperparathyroidism and malignancy.• Patients can present with ossifying fibromas of the jaw, hypercalcaemia or malignancy.• A high index of suspicion is required for the underlying diagnosis to be recognised.• Management involves screening of family members.
The latest (4th) edition of the World Health Organization Classification of Head and Neck tumours has recently been published with a number of significant changes across all tumour sites. In particular, there has been a major attempt to simplify classifications and to use defining criteria which can be used globally in all situations, avoiding wherever possible the use of complex molecular techniques which may not be affordable or widely available. This review summarises the changes in Chapter 8: Odontogenic and maxillofacial bone lesions. The most significant change is the re-introduction of the classification of the odontogenic cysts, restoring this books status as the only text which classifies and defines the full range of lesions of the odontogenic tissues. The consensus group considered carefully the terminology of lesions and were concerned to ensure that the names used properly reflected the best evidence regarding the true nature of specific entities. For this reason, this new edition restores the odontogenic keratocyst and calcifying odontogenic cyst to the classification of odontogenic cysts and rejects the previous terminology (keratocystic odontogenic tumour and calcifying cystic odontogenic tumour) which were intended to suggest that they are true neoplasms. New entities which have been introduced include the sclerosing odontogenic carcinoma and primordial odontogenic tumour. In addition, some previously poorly defined lesions have been removed, including the ameloblastic fibrodentinoma, ameloblastic fibro-odontoma, which are probably developing odontomas, and the odontoameloblastoma, which is not regarded as an entity. Finally, the terminology “cemento” has been restored to cemento-ossifying fibroma and cemento-osseous dysplasias, to properly reflect that they are of odontogenic origin and are found in the tooth-bearing areas of the jaws.
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